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Functional Roles of Phospholipids of Synaptosomal Membrane

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Function and Metabolism of Phospholipids in the Central and Peripheral Nervous Systems

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 72))

Abstract

Synaptosomal plasma membrane (SPM) is not merely a stable boundary structure separating the cytoplasmic materials from their surrounding, it is also functionally active through proper arrangement and interactions with its component molecules, mainly proteins, lipids, and polysaccharides. Located within the matrix of SPM, there are cellular enzymes, such as (Na + K)-ATPase and acetylcholinesterase as well as other types of proteins which are constantly engaged in trans-membrane transport. Thus SPM is an important type of membrane in brain since it can provide a unique system for studying the relationship between membrane structure and function.

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References

  • Abdel-Latif, A. A. (1973) Meth. Neurochem, 5:147–188

    Google Scholar 

  • Abood, L. G, (1969) In “Neuroscience Research” (S. Ehrenpreisand O. C. Solnitzkey, eds.) Academic Press, New York.

    Google Scholar 

  • Albers, R. W. (1967) Ann. Rev. Biochem. 36:727.

    Article  Google Scholar 

  • Albers, R. W., Fahn, S. and Koval, G. J. (1963) Proc. Nat. Acad. Sci. U.S.A. 50:474–480.

    Article  Google Scholar 

  • Armstrong, C. M. and Binstock, L. (1964) J. Gen. Physical. 48: 279–295.

    Article  Google Scholar 

  • Banker, G., Grain, B. and Cotman, C. W. (1972) Brain Res. 42: 508–513.

    Article  Google Scholar 

  • Bloj, B., Morero, R. D., Farias, R. N. and Trucco, R. E. (1973) Biochem. Biophys. Acta. 311:67–79.

    Article  Google Scholar 

  • Bonting, S. L. (1970) “Membrane and Ion Transport” (E. D. Bittas, ed.) Vol. 1, Wiley and Interscience, New York, p. 257.

    Google Scholar 

  • Breckenridge, W. C., Gombos, G. and Morgan, I. G. (1971) Brain Res. 33:581.

    Article  Google Scholar 

  • Cotman, C. W. and Mathews, D. A. (1971) Biochem. Biophys. Acta. 249:380–394.

    Article  Google Scholar 

  • Davidson, F. M. and Long, C. (1958) Biochem. J. 69:458–466.

    Google Scholar 

  • DeHaas, G. H., Mulder, I. and van Deenan, L. L. M. (1960) Biochem. Biophys. Res. Comm. 3:287–291.

    Article  Google Scholar 

  • Fairbanks, G., Steck, T. L. and Wallach, D. F. H. (1971) Biochem. 10:2606–2617.

    Article  Google Scholar 

  • Galli, C., Spagnuolo, C. and Bosisio, E. (1975) Chapter in this volume.

    Google Scholar 

  • Glynn, I. M. (1968) Brit. Med. Bull. 24:165–167.

    Google Scholar 

  • Goldman, S, S. and Albers, R. W. (1973) J. Biol. Chem. 248:867- 874.

    Google Scholar 

  • Gray, E. G. and Whittaker, V. P. (1962) J. Anat. (London). 96:79–88.

    Google Scholar 

  • Gullis, R. J. and Rowe, C. E. (1975) Biochem. J. 148:197–208

    Google Scholar 

  • Hanahan, D. J., Brockerhoff, J. H. and Barron, E. J. (1960) J. Biol. Chem. 235:1917–1923.

    Google Scholar 

  • Hawthorne, J. N. and Kai, M. (1970) In “Handbook of Neurochemistry” (A. Lajtha, ed.). Plenum Press, New York, Vol. 3, p. 491–508.

    Google Scholar 

  • Hegyvary, C. and Post, R. L. (1971) J. Biol. Chem. 246:5234–5240.

    Google Scholar 

  • Hokin, L. E. and Hokin, M. R. (1963) Ann. Rev. Biochem. 32:553- 578.

    Article  Google Scholar 

  • Horrocks, L. A., Sun, G. Y. and D’Amato, R. A. (1975) In “Neurobiology and Aging” (J. M. Ordy and K. R. Brizzee, eds.). Plenum Press, New York, p. 359–368.

    Google Scholar 

  • Israel, Y., Kalant, H. and LeBlanc, A. E. (1969) Biochem. J. 100: 27–33.

    Google Scholar 

  • Israel-Jacord, Y. and Kalant, H. (1969) J. Cell Comp. Physiol. 66:127–132.

    Google Scholar 

  • Jardetzky, O. (1969) Nature 211:696.

    Google Scholar 

  • Kennedy, E. P. (1957) Ann. Rev. Biochem. 26. 119–148.

    Article  Google Scholar 

  • Molinoff, P. B. and Axelrod, J. (1971) Ann. Rev. Biochem. 40: 465–500.

    Article  Google Scholar 

  • Moore, J. W., Albricht, A. and Takata, M. (1964) J. Gen. Physical. 48. 279–295.

    Article  Google Scholar 

  • Morgan, I. G., Wolfe, S., Mandel, P. and Gombos, G. (1971) Biochem. Biophys. Acta 241:737–751.

    Article  Google Scholar 

  • Post, R. L. (1968) “Regulatory Function of Biological Membranes” (J. Janefelt, ed.), Elsevier Pub. Co., Amsterdam, p. 163–176.

    Google Scholar 

  • Post, R. L., Hegyvary, C. and Kume, S. (1972) J. Biol. Chem. 247:6530–6540.

    Google Scholar 

  • Post, R. L., Kume, S., Tobin, T., Orcutt, B. and Sen, A. K. (1969) J. Gen. Physical 54:306–326.

    Article  Google Scholar 

  • Post, R. L., Sen, H. K. and Rosenthal, A. S. (1965) J. Biol. Chem. 240:1437–1445.

    Google Scholar 

  • Sun, A. Y. (1971) Trans. Am. Soc. Neurochem. 2:112.

    Google Scholar 

  • Sun, A. Y. (1972) Biochem. Biophys. Acta 266:350–360.

    Article  Google Scholar 

  • Sun, A. Y. (1973) Abstract, presented at the 4th International Meeting of the International Society for Neurochemistry, Tokyo, Japan.

    Google Scholar 

  • Sun, A. Y. (1973) Abstract: 9th Int’l Congress of Biochem. S tockholm, Sweden.

    Google Scholar 

  • Sun, A. Y. (1974) J. Neurochem. 22:551–556.

    Article  Google Scholar 

  • Sun, A. Y. (1975) Alcohol-menibrane Interaction. I. Reversibility. Ann. New York Acad. Sci. (In Press).

    Google Scholar 

  • Sun, A. Y., Hopkins, C. A., Burke, J. P. and Tumbleson, M. E. (1975) Abstract: Fifth Int. Meeting of ISN.

    Google Scholar 

  • Sun, A. Y. and Samorajski, T. (1970) J. Neurochem. 17:1365–1372.

    Article  Google Scholar 

  • Sun, A. Y., Sun, G. Y. and Samorajski, T. (1971) J. Neurochem. 18:1711–1718.

    Article  Google Scholar 

  • Sun, G. Y. (1972). J. Lipid Res. 13:56–62.

    Google Scholar 

  • Sun, G. Y. (1973). Abstract: ICBL.

    Google Scholar 

  • Sun, G. Y. (1973). J. Neurochem. 21:1083–1092.

    Article  Google Scholar 

  • Sun, G. Y. and Horrocks, L. A. (1968) Lipids 3:91–95.

    Google Scholar 

  • Sun, G. Y. and Horrocks, L. A. (1969) J. Neurochem. 16:181–189.

    Article  Google Scholar 

  • Sun, G. Y. and Horrocks, L. A. (1971) Neurochem. 18:1963–1969.

    Article  Google Scholar 

  • Sun, G. Y. and Horrocks, L. A. (1973) J. Lipid Res. 14:206–214.

    Google Scholar 

  • Sun, G. Y. and Samorajski, T.(1973). Biochem. Biophys. Acta. 316:19–27.

    Article  Google Scholar 

  • Sun, G. Y. and Sun, A. Y. (1972) Biochem. Biophys. Acta 280:306–373

    Article  Google Scholar 

  • Sun, G. Y. and Sun, A. Y. (1975), Abstract: Fifth Int. Meeting ISN.

    Google Scholar 

  • Sun, G. Y. Winniczek, H., Go, J. and Sheng, S. L. (1975) Lipids 10:365–373

    Article  Google Scholar 

  • Skou, J. C. (1957) Biochem. Biophys. Acta, 23. 394–401.

    Article  Google Scholar 

  • Skou, J. C. (1965) Physiol. Rev. 45. 596–617.

    Google Scholar 

  • Stahl, W. L. (1973) Arch. Biochem. Biophys. 154:56–67.

    Article  Google Scholar 

  • Tanaka, R. (1969) J. Neurochem. 16:1301–1307.

    Article  Google Scholar 

  • Tobin, T., Akera, T., Badkin, S. I. and Brody, T. M. (1973) Mol. Pharmacol. 9. 336–349.

    Google Scholar 

  • Van den Bosch, H., Postema, N. M., DeHaas, G. H. and van Deenan, L. L. M. (1965) Biochem. Biophys. Acta 98:657–659.

    Article  Google Scholar 

  • Webster, G. R. (1967) Biochem. J. 102;373–380.

    Google Scholar 

  • Wheeler, K. P. and Whittan, R. (1964) Biochem. J. 93:348.

    Google Scholar 

  • Yau, T. M. and Sun, G. Y. (1973) Lipids 8:410–414.

    Article  Google Scholar 

  • Yau, T. M. and Sun, G. Y. (1974) J. Neurochem. 23:99–104.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Sinclair Comparative Medicine Research Farm, University of Missouri, 65201, Columbia, Missouri, USA

    Albert Y. Sun & Grace Y. Sun

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  1. Albert Y. Sun
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  2. Grace Y. Sun
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Editor information

Editors and Affiliations

  1. University of Perugia, Perugia, Italy

    Giuseppe Porcellati

  2. Florence, Italy

    Luigi Amaducci

  3. University of Milan, Milan, Italy

    Claudio Galli

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© 1976 Plenum Press, New York

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Sun, A.Y., Sun, G.Y. (1976). Functional Roles of Phospholipids of Synaptosomal Membrane. In: Porcellati, G., Amaducci, L., Galli, C. (eds) Function and Metabolism of Phospholipids in the Central and Peripheral Nervous Systems. Advances in Experimental Medicine and Biology, vol 72. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0955-0_16

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  • DOI: https://doi.org/10.1007/978-1-4684-0955-0_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0957-4

  • Online ISBN: 978-1-4684-0955-0

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