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Evidence of a Catalytic Role of Heparin in Anticoagulation Reactions

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Heparin

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 52))

Abstract

The nature of heparin involvement in the inhibition of factor Xa or thrombin by their natural plasma inhibitor has not been completely elucidated. This report describes some of the properties of heparin that may be important in this inhibition reaction.

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References

  1. Bachmann, F., Duckert, F. and Roller, F., Throm. Diath. Haemorrh., 2 (1958) 24.

    CAS  Google Scholar 

  2. Barton, P.G., Jackson, C.M. and Hanahan, D.J., Nature, 214 (1967) 923.

    Article  PubMed  CAS  Google Scholar 

  3. Cuatrecasas, P., J. Biol. Chem., 245 (1970) 3059.

    PubMed  CAS  Google Scholar 

  4. Danishefsky, I. and Tzeng, F., Thomb. Research, 4 (1974) 237.

    Article  CAS  Google Scholar 

  5. Duckert, F., Yin, E.T. and Straub, W., Prot. Biol. Fluids Proc. Colloq. Bruges, 41 (1960).

    Google Scholar 

  6. Fujikawa, K., Legaz, M.E. and Davie, E.W., Biochemistry, 11 (1972) 4892.

    Article  PubMed  CAS  Google Scholar 

  7. Gitel, S.W., Owen, W.G., Esmon, C.T. and Jackson, C.M., Proc. Natl. Acad. Sci. US, 70 (1973) 1344.

    Google Scholar 

  8. Hjort, P., Rapaport, S.I. and Owren, P.A., J. Lab. Clin. Med., 46 (1955) 89.

    PubMed  CAS  Google Scholar 

  9. Jackson, C.M., Biochemistry, 11 (1972) 4873

    Article  PubMed  CAS  Google Scholar 

  10. Jobin, F. and Esnouf, M.P., Biochem. J., 102 (1967) 666.

    PubMed  CAS  Google Scholar 

  11. Magnusson, S., in The Enzymes (Ed. Boyer) Academic Press, New York, 3 (1971) p. 277.

    Google Scholar 

  12. Van Lenten, V. and Ashwell, G., J. Biol. Chem., 246 (1970) 1889.

    Google Scholar 

  13. Wilson-Gentry, P. and Alexander, B., Fed. Proc. Abstracts, 57th Meet., 1973

    Google Scholar 

  14. Yin, E.T. and Wessler S., J. Biol. Chem., 243 (1968) 112.

    PubMed  CAS  Google Scholar 

  15. Yin, E.T., Wessler, S. and Butler, J.V., J. Lab. Clin. Med., 81 (1973) 298.

    PubMed  CAS  Google Scholar 

  16. Yin, E.T., Wessler, S. and Stoll, P.J., J. Biol. Chem., 246 (1971) 3694.

    PubMed  CAS  Google Scholar 

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© 1975 Plenum Press, New York

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Gitel, S.N. (1975). Evidence of a Catalytic Role of Heparin in Anticoagulation Reactions. In: Bradshaw, R.A., Wessler, S. (eds) Heparin. Advances in Experimental Medicine and Biology, vol 52. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0946-8_20

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  • DOI: https://doi.org/10.1007/978-1-4684-0946-8_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0948-2

  • Online ISBN: 978-1-4684-0946-8

  • eBook Packages: Springer Book Archive

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