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Plasmid Replication

  • Chapter
DNA Synthesis

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 17))

Abstract

Bacterial plasmids offer many advantages for the study of DNA replication and its control. These extrachromosomal genetic elements have been discovered in over 40 different bacterial genera and they display a wide variety of phenotypic characteristics (1–4). Moreover, within an individual taxonomic grouping of bacteria, such as the Enterobacteriaceae, many different types of plasmids have been identified and characterized. These plasmids may differ in their molecular size, DNA base composition, and replication properties (1–7). As would be expected, larger plasmids are more diverse in their functions, since they carry a larger number of genes. There is recent evidence, however, that only a relatively small region of a plasmid specifies the genetic information for its autonomous replication (8–11).

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References

  1. Novick, R. (1969) Bacteriol. Rev. 33:210–264

    PubMed  CAS  Google Scholar 

  2. Meynell, G. (1973) Bacterial Plasmids, M.I.T. Press, Cambridge, Mass.

    Google Scholar 

  3. Falkow, S. (1975) Infectious Multiple Drug Resistance. Pion, Ltd., London.

    Google Scholar 

  4. Lewin, B. (1977) Gene Expression-3. Plasmids and Phages. John Wiley and Sons, New York.

    Google Scholar 

  5. Clowes, R. (1972) Bacteriol. Rev. 36:361–405

    PubMed  CAS  Google Scholar 

  6. Davies, J.E. and Rownd, R.H. (1972) Science 176:758–768

    Article  PubMed  CAS  Google Scholar 

  7. Helinski, D.R. (1973) Ann. Rev. Microbiol. 27:437–470

    Article  CAS  Google Scholar 

  8. Timmis, K., Cabello, F. and Cohen, S.N. (1975) Proc. Natl. Acad. Sci. USA 72:2242–2246

    Article  PubMed  CAS  Google Scholar 

  9. Lovett, M.A. and Helinski, D.R. (1976) J. Bacteriol. 127: 982–987

    PubMed  CAS  Google Scholar 

  10. Mickel, S. and Bauer, W. (1976) J. Bacteriol. 127:644–655

    PubMed  CAS  Google Scholar 

  11. Taylor, D.P., Greenberg, J. and Rownd, R.H. (1977) J. Bacteriol. 132:

    Google Scholar 

  12. Datta, N. (1975) In: Microbiology - 1974 (ed. D. Schlessinger) American Society for Microbiology, Washington, D.C. pp9–15

    Google Scholar 

  13. Rownd, R.H., Perlman, D. and Goto, N. (1975) In: Microbiology —1974 (ed. D. Schlessinger) American Society for Microbiology, Washington, D.C. pp76–94

    Google Scholar 

  14. Rownd, R.H., Perlman, D., Womble, D.D., Taylor, D.P., Morris, C.F. and Hill, W.E. (1975) In: Microbial Drug Resistance (ed. S. Mitsuhashi and H. Hashimoto) University of Tokyo Press, Tokyo. pp27–50

    Google Scholar 

  15. Perlman, D. and Rownd, R.H. (1976) Nature 259:281–284

    Article  PubMed  CAS  Google Scholar 

  16. Rownd, R.H., Perlman, D., Hashimoto, H., Mickel, S., Appelbaum, E. and Taylor, D. (1973) In: Cellular Modification and Genetic Transformation by Exogenous Nucleic Acids (eds. R.F. Beers, Jr. and R.C. Tilgham) The Johns Hopkins University Press, Baltimore. pp115–128

    Google Scholar 

  17. Rownd, R.H., Goto, N., Appelbaum, E.R. and Perlman, D. (1975) In: Microbial Drug Resistance (eds. S. Mitsuhashi and H. Hashimoto) University of Tokyo Press, Tokyo. pp3–25

    Google Scholar 

  18. Helinski, D., Lovett, M., Williams, P., Katz, L., Collins, J., Kupersztoch-Portnoy, Y., Sato, S. Leavitt, R., Sparks, R., Hershfield, V., Gainey, D. and Blair, D. (1975) In: DNA Synthesis and Its Regulation. (eds. M. Goulian and P. Hanawalt) W.A. Benjamin, Inc., Menlo Park, California. pp514–536

    Google Scholar 

  19. Veltkamp, E. and Nijkamp, H.J. (1977) In: Plasmids: Medical and Theoretical Aspects. Springer-Verlag, Berlin. pp203–212

    Google Scholar 

  20. Bazaral, M. and Helinski, D.R. (1970) Biochemistry 9:399–406

    Article  PubMed  CAS  Google Scholar 

  21. Achtman, M. and Helmuth, R. (1975) In: Microbiology - 1974 (ed. D. Schlessinger) American SOciety for Microbiology, Washington, D.C. pp95–103

    Google Scholar 

  22. Rownd, R. (1969) J. Mol. Biol. 44:387–402

    Article  PubMed  CAS  Google Scholar 

  23. Terawaki, Y. and Rownd, R. (1972) J. Bacteriol. 109:492–498

    PubMed  CAS  Google Scholar 

  24. Lark, K.G. (1969) Ann. Rev. Biochem. 38:569–604

    Article  PubMed  CAS  Google Scholar 

  25. Clewell, D.B., Evenchik, B. and Cranston, J.W. (1972) Nature New Biol. 237:29–31

    PubMed  CAS  Google Scholar 

  26. Veltkamp, E., Barendsen, W. and Nijkamp, H.J. (1974) J. Bacteriol. 118:165–174

    PubMed  CAS  Google Scholar 

  27. Hershfield, V., Boyer, H.W., Chow, L. and Helinski, D.R. (1976) J. Bacteriol. 126:447–453

    PubMed  CAS  Google Scholar 

  28. Kline, B.C. and Helinski, D.R. (1971) Biochemistry 10: 4975–4980

    Article  PubMed  CAS  Google Scholar 

  29. Rownd, R., Kasamatsu, H. Acad. Sci. 182:188–206

    Google Scholar 

  30. Terawaki, Y., Nakaya, R. and Mickel, S. (1971) Ann. N.Y. and Rownd, R. (1974) J. Bacteriol.117:687–695

    Google Scholar 

  31. Morris, C., Hashimoto, H., Mickel, S. and Rownd, R. (1974) J. Bacteriol. 118:855–866

    PubMed  CAS  Google Scholar 

  32. Womble, D.D. and Rownd, R.H. (1978) Submitted to Plasmid

    Google Scholar 

  33. Hirota, Y., Mordoh, J., Scheffler, I. and Jacob, F. (1972) Fed. Proc. 31:1422–1427

    PubMed  CAS  Google Scholar 

  34. Gefter, M. (1975) Ann. Rev. Biochem. 44:45–78

    Article  PubMed  CAS  Google Scholar 

  35. Collins, J., Williams, P. and Helinski, D.R. (1975) Molec. Gen. Genet. 136:273–289

    Article  PubMed  CAS  Google Scholar 

  36. Arai, T. and Clowes, R. (1975) In: Microbiology - 1974 (ed. D. Schlessinger) American Society for Microbiology, Washington, D.C. pp141–155

    Google Scholar 

  37. Helinski, D.R. and Clewell, D.B. (1971) Ann. Rev. Biochem. 40:899–942

    Article  PubMed  CAS  Google Scholar 

  38. Tomizawa, J., Ohmori, H. and Bird, R.E. (1977) Proc. Natl. Acad. Sci. USA 74:1865–1869

    Article  PubMed  CAS  Google Scholar 

  39. Dougan, G. and Sherratt, D. (1977) Molec. Gen. Genet. 151: 151–160

    Article  PubMed  CAS  Google Scholar 

  40. Inselburg, J. (1977) J. Bacteriol. 132:332–340

    PubMed  CAS  Google Scholar 

  41. Stonington, O. and Pettijohn, D. (1971) Proc. Natl. Acad. Sci. USA 68:6–9

    Article  PubMed  CAS  Google Scholar 

  42. Worcel, A. and Burgi, E. (1972) J.

    Google Scholar 

  43. Kline, B.C. (1975)J. Bacteriol. 121:165–172

    PubMed  CAS  Google Scholar 

  44. Cress, D.E. and Miller, J.R. and Kline, B.C. (1976) J. Bacteriol. 125:635–642

    PubMed  CAS  Google Scholar 

  45. Nordström, K., Ingram, L. and Landbäck, A. (1972) J. Bacteriol. 110:562–569

    PubMed  Google Scholar 

  46. Kool, A.J. and Nijkamp, H.J. (1974) J. Bacteriol. 120: 569–578

    PubMed  CAS  Google Scholar 

  47. Jacob, F., Brenner, S. and Cuzin, F. (1963) Cold Spring Harbor Symp. Quant. Biol. 28:329–348

    CAS  Google Scholar 

  48. Kingsbury, D.T. and Helinski, D.R. (1973) J. Bacteriol. 114: 1116–1124

    PubMed  CAS  Google Scholar 

  49. Perlamn, D. and Rownd, R.H. (1975) Molec Gen. Genet. 138: 281–291

    Google Scholar 

  50. Barnes, M.H. and Rownd, R. (1972) J. Bacteriol. 111:750–757

    PubMed  CAS  Google Scholar 

  51. Crosa, J.H., Luttropp, L.K., Heffron, F. and Falkow, S. (1975) Molec. Gen. Genet. 140:39–50

    Article  PubMed  CAS  Google Scholar 

  52. Lovett, M.A., Katz, L. and Helinski, D.R. (1974) Nature 251:337–340

    Article  PubMed  CAS  Google Scholar 

  53. Womble, D.D., Warren, R.L. and Rownd, R.H. (1976) Nature 264:676–678

    Article  PubMed  CAS  Google Scholar 

  54. Kasamatsu, H. and Vinograd, J. (1974) Ann. Rev. Biochem. 43:695–719

    Article  PubMed  CAS  Google Scholar 

  55. Womble, D.D., Warren, R.L. and Rownd, R.H. (1978) Submitted to J. Bacteriol.

    Google Scholar 

  56. Crosa, J.H., Luttropp, L.K. and Falkow, S. (1976) Nature 261:516–519

    Article  PubMed  CAS  Google Scholar 

  57. Cabello, F., Timmis, K. and Cohen, S.N. (1976) Nature 259: 285–290

    Article  PubMed  CAS  Google Scholar 

  58. Eichenlaub, R., Figurski, D. and Helinski, D. (1977) Proc. Natl. Acad. Sci. USA 74:1138–1141

    Article  CAS  Google Scholar 

  59. Lovett, M.A., Sparks, R.B. and Helinski, D.R. (1975) Proc. Natl. Acad. Sci. USA 72:2905–2909

    Article  CAS  Google Scholar 

  60. Crosa, J.H., Luttropp, L.K., Thomas, M. and Falkow, S. (1978) In: Microbiology - 1978. (eds. J. Davies and R. Novick) American Society for Microbiology, Washington, D.C.

    Google Scholar 

  61. Palchaudhuri, S. and Maas, W. (1978) In: Microbiology - 1978 (eds. J. Davies and R. Novick) American Society for Microbiology, Washington, D.C.

    Google Scholar 

  62. Warren, R.L., Womble, D.D., Tanaka, N., Barton, C.R.,Scallon, S., Cramer, J.H. and Rownd, R.H. (1977) In: Plasmids: Medical and Theoretical Aspects. Springer-Verlag, Berlin. pp253–264

    Google Scholar 

  63. Warren, R.L., Womble, D.D., Barton, C.R., Easton, A.E. and Rownd, R.H. (1978) In: Microbiology - 1978 (eds. J. Davies and R. Novick) American Society for Microbiology, Washington, D.C.

    Google Scholar 

  64. Greenberg, J. and Rownd, R.H. (1978) Submitted to J. Bacteriol.

    Google Scholar 

  65. Hashimoto, H. and Rownd, R. (1975) J. Bacteriol. 123:56–58

    PubMed  CAS  Google Scholar 

  66. Rownd, R.H., Perlman, D., Goto, N. and Appelbaum, E.R. (1975) In: DNA Synthesis and Its Regulation (eds. M. Goulian and P. Hanawalt). W.A. Benjamin, Inc., Menlo Park, Calfornia. pp537–559

    Google Scholar 

  67. Tanaka, N., Cramer, J.H. and Rownd, R.H. (1976) J. Bacteriol. 127:619–636

    CAS  Google Scholar 

  68. Rownd, R.H., Miki, T., Appelbaum, E.R., Miller, J.R., Finkelstein, M. and Barton, C.R. (1978) In: Microbiology – 1978 (eds. J. Davies and R. Novick) American Society for Microbiology, Washington, D.C.

    Google Scholar 

  69. Watanabe, T. and Ogata, Y. (1970) J. Bacteriol. 102:363–368

    PubMed  CAS  Google Scholar 

  70. Finkelstein, M. and Rownd, R.H. (1978) Submitted for publication.

    Google Scholar 

  71. Clewell, D.B., Yagi, Y. and Bauer, B. (1975) Proc. Natl. Acad. Sci. USA 72:1720–1724

    Article  PubMed  CAS  Google Scholar 

  72. Broda, P., Bayley, S.A., Duggleby, C.J., Worsey, M.J. and Williams, P.A. (1978) In: Microbiology - 1978. (eds. J. Davies and R. Novick) American Society for Microbiology, Washington, D.C.

    Google Scholar 

  73. Huffman, G., Miki, T. and Rownd, R.H. Manuscript in preparation.

    Google Scholar 

  74. Anderson, R.A. and Roth, J.R. (1977) Ann. Rev. Microbiol. 31:473–505

    Article  CAS  Google Scholar 

  75. Miki, T., Easton, A.E. and Rownd, R.H. (1977) Molec. Gen. Genet. (in press)

    Google Scholar 

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    Authors
    1. Robert H. Rownd
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    Editors and Affiliations

    1. Imperial Cancer Research Fund, London, England

      Ian Molineux

    2. University of Paris, Paris, France

      Masamichi Kohiyama

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    © 1978 Plenum Press, New York

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    Rownd, R.H. (1978). Plasmid Replication. In: Molineux, I., Kohiyama, M. (eds) DNA Synthesis. NATO Advanced Study Institutes Series, vol 17. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0844-7_54

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    • DOI: https://doi.org/10.1007/978-1-4684-0844-7_54

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