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The Three DNA Polymerases of Animal Cells: Properties and Functions

  • Chapter
DNA Synthesis

Part of the book series: NATO Advanced Study Institutes Series ((NSSA,volume 17))

Abstract

For the understanding of the events leading to the advancement of the DNA growing fork in animal cells, a description of the molecules involved in this process is essential. The search for these molecules is oriented by the wealth of information obtained in prokaryotic systems, where the cross-evidence from the biochemical data and the analysis of conditional lethal mutants altered in DNA replication has allowed the beginning of a description of the complex series of reactions occurring at the growing point. From these systems it is apparent that the basic polymerization reaction is assured by a DNA dependent DNA polymerase (1).

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Author information

Authors and Affiliations

  1. Laboratorio di Genetica Biochimica ed Evoluzionistica, Consiglio Nazionale delle Ricerche, Via S. Epifanio, 14, 27100, Pavia, Italy

    Arturo Falaschi & Silvio Spadari

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  1. Arturo Falaschi
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  2. Silvio Spadari
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Editors and Affiliations

  1. Imperial Cancer Research Fund, London, England

    Ian Molineux

  2. University of Paris, Paris, France

    Masamichi Kohiyama

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© 1978 Plenum Press, New York

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Falaschi, A., Spadari, S. (1978). The Three DNA Polymerases of Animal Cells: Properties and Functions. In: Molineux, I., Kohiyama, M. (eds) DNA Synthesis. NATO Advanced Study Institutes Series, vol 17. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0844-7_38

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  • DOI: https://doi.org/10.1007/978-1-4684-0844-7_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0846-1

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