Skip to main content
SpringerLink
Log in
Book cover

Inorganic and Nutritional Aspects of Cancer pp 259–279Cite as

The Arsenic Problems

  • Chapter

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 91))

Abstract

Arsenophobia has held sway over civilized governments throughout this century. Because of the still unproven association between arsenic (As) and cause of cancer, arsenophobia has gained strength to the point that many safe uses of arsenicals have been abandoned. Even the production of arsenic trioxide (AS2O3) is in jeopardy. No arsenical has been shown to cause cancer, but arsenicals have proven anticancer value. Evidence suggests that As is an essential nutrient and that the level of As in the United States’ and Canadian diets may be too low. Due to the long history of errors in judgment about “arsenic” and the strength of the traditional dogmas, there are many problems to be solved; hence, the above title.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Lasagna, L., Perspectives Biol. Medicine, Page 537, Summer, 1976.

    Google Scholar 

  2. Butlin, H., British Medical Journal 2, Page 66, 1892.

    Article  PubMed  CAS  Google Scholar 

  3. Woodhouse, D. L., Progress in the Biological Sciences in Relation to Dermatology, A. Rock, Editor, University Press, Cambridge, England, Page 356, 1960.

    Google Scholar 

  4. Frost, D. V., Nutrition Review 18, Page 129, 1960.

    Article  CAS  Google Scholar 

  5. Kennaway, E., Lancet 2, Page 769, 1942.

    Article  Google Scholar 

  6. Kennaway, E., Lancet 1, Page 599, 1943.

    Article  Google Scholar 

  7. Hueper, W. C., Lancet 1, Page 538, 1943.

    Article  Google Scholar 

  8. Heiger, I., Carcinogenesis, Academic Press, New York, 1961.

    Google Scholar 

  9. Woglom, W. H., Arch. Path. Laboratory Medicine 2, Page 533, 1926.

    Google Scholar 

  10. Bierich, R., Klin. Wchnschr. 1, Page 2272, 1922.

    Article  Google Scholar 

  11. Satterlee, H. S., New England J. Medicine 263, Page 676, 1960.

    Article  CAS  Google Scholar 

  12. Frost, D. V., Federation Proceedings 26, Page 194, 1967.

    PubMed  CAS  Google Scholar 

  13. IARC Monograph-Evaluation of Carcinogenic Risk to Man, World Health Organization, Geneva, 1973.

    Google Scholar 

  14. Nutt, W. H., Beattie, J. M. and Pye-Smith, R. J., Lancet 2, pp 210 and 282, 1913.

    Article  Google Scholar 

  15. Neubauer, O., Brit. J. Cancer 1, Page 192, 1947.

    Article  PubMed  CAS  Google Scholar 

  16. Goodman, L. S. and Gilman, A., Pharmacologic Basis of Therapeutics, MacMillan, New York, 1935.

    Google Scholar 

  17. Knock, F. E., et al., JAMA 224, Page 129, 1973.

    Article  PubMed  CAS  Google Scholar 

  18. Knock, F. E., et al., Oncology 30, Page 1, 1974.

    Article  PubMed  CAS  Google Scholar 

  19. Schwarz, K., Federation Proceedings 33, Page 1748, 1974.

    PubMed  CAS  Google Scholar 

  20. Frost, D. V., World’s Poultry Science Journal 21, Page 139, 1965.

    Article  PubMed  CAS  Google Scholar 

  21. Frost, D. V., World Rev. Pest Control 6, Page 9, 1970.

    Google Scholar 

  22. Hueper, W. C. and Payne, W. W., Arch. Environmental Health 5, Page 445, 1962.

    CAS  Google Scholar 

  23. Hueper, W. C., Occupational and Environmental Cancer of the Respiratory System, Springer-Verlag, New York, 1966.

    Google Scholar 

  24. Shamberger, R. J. and Frost, D. V., Canadian Medical Association Journal, 100, Page 682, 1969.

    PubMed  CAS  Google Scholar 

  25. Shamberger, R. J. and Willis, C. E., CRC Critical Review, Clinical Laboratory Science 2 Page 211, 1971.

    Article  CAS  Google Scholar 

  26. Frost, D. V. and Ingvoldstad, D., Chemica Scripta 8A, Page 96, 1975.

    CAS  Google Scholar 

  27. Schrauzer, G. N., Bioinorganic Chemistry 5, Page 275, 1976.

    Article  PubMed  CAS  Google Scholar 

  28. Hill, C. H., Federation Proceedings 34, Page 2096, 1975.

    PubMed  CAS  Google Scholar 

  29. Frost, D. V., Proceedings Cornell Nutrition Conference, Page 31, 1967.

    Google Scholar 

  30. Levander, O. A. and Bauman, C. A., Toxicology Appl. Pharmacology 9, PP 98 and 106, 1966.

    Article  CAS  Google Scholar 

  31. Levander, O. A. and Argrett, L. C., Toxicology Applied Pharmacology 14, Page 308, 1969.

    Article  CAS  Google Scholar 

  32. Schwarz, K., Vitamins and Hormones 20, Page 463, 1962.

    Article  CAS  Google Scholar 

  33. Schrauzer, G. N. and Ishmael, D., Annals Clinical Laboratory Science 4, Page 441, 1974.

    CAS  Google Scholar 

  34. Frost, D. V., Feedstuffs 47(14), Page 20, 1975.

    Google Scholar 

  35. Pinto, S. S. and Nelson, K. W., Annual Review Pharmacology 16, Page 95, 1976.

    Article  CAS  Google Scholar 

  36. Bencko, V. and Symon, K., Atmos. Environment 4, Page 157, 1970.

    Article  CAS  Google Scholar 

  37. Kanisawa, N. and Schroeder, H. A., Cancer Research 27, Page 1192, 1967.

    PubMed  CAS  Google Scholar 

  38. Kanisawa, N. and Schroeder, H. A., Cancer Research 29, Page 892, 1969.

    PubMed  CAS  Google Scholar 

  39. Smoking and Health, PHS Publication 1103, USGPO, Washington, 1974.

    Google Scholar 

  40. Nielsen, F. H., et al., Federation Proceedings 34(3), Abstr.3987, 1975.

    Google Scholar 

  41. Hove, E., et al., American J. Physiology 124, Page 205, 1938.

    CAS  Google Scholar 

  42. Skinner, J. T. and McHargue, J. S., American J. Physiology 145, Page 500, 1946.

    CAS  Google Scholar 

  43. Liebscher, K. and Smith, H., Arch. Environmental Health 17, Page 881, 1968.

    CAS  Google Scholar 

  44. Chan, T., et al., J. Biolog. Chemistry 244, Page 2883, 1969.

    CAS  Google Scholar 

  45. Dilley, R. A., Arch. Biochem. Biophysics 137, Page 270, 1970.

    Article  CAS  Google Scholar 

  46. Peoples, S. A., The Use of Drugs in Animal Feeds, National Academy Science, Washington, D. C., Page 77, 1969.

    Google Scholar 

  47. Sullivan, T. W. and Al-Timimi, A. A., Poultry Science 59, Page 1582, 1972.

    Article  Google Scholar 

  48. Stoklasa, J., Annals Agronomy 23, Page 471, 1897.

    CAS  Google Scholar 

  49. Stewart, J. and Smith, E. S., Soil Science 14, Page 111, 1922.

    Article  CAS  Google Scholar 

  50. Woolson, E. A., et al., Soil Science Society America 37, Page 254, 1973.

    Article  Google Scholar 

  51. Goldshmidt, V. M., Geochemistry, Oxford-Clarendon Press, Oxford, 1954.

    Google Scholar 

  52. Greaves, J. E., J. Agricultural Research 6, Page 389, 1916.

    CAS  Google Scholar 

  53. Reitz, H. J., Proceedings Florida Horticultural Society 49, 1949; 83, Page 15, 1970.

    Google Scholar 

  54. McNulty, I. R. and Rhodes, E. A., Utah Academy Proceedings 32, Page 125, 1955.

    CAS  Google Scholar 

  55. Hiltbold, A. E., Report to EPA Arsenic Advisory Committee, 1973.

    Google Scholar 

  56. Done, A. H. and Peart, A. J., Clinical Toxicology 4, Page 343, 1971.

    Article  PubMed  CAS  Google Scholar 

  57. Ott, M., et al., Arch. Environmental Health 29, Page 250, 1974.

    CAS  Google Scholar 

  58. Criteria for a Recommended Standard-Occupational Exposure to Inorganic Arsenic, NIOSH, Washington, 1973; Federal Register 40, Page 3391, 1975.

    Google Scholar 

  59. Carnow, B. W., Editor, Health Effects of Occupational Lead and Arsenic Exposure, USGPO, Washington, D. C., 1976.

    Google Scholar 

  60. Ferguson, J. F. and Gavis, J., Water Research 6, Page 1259, 1974.

    Article  Google Scholar 

  61. Sandberg, G. R. and Allen, I. K., ACS Symp. Series 1975 (Arsenical Pesticide Symposium 1974), Page 70; CA 82, 119631Q, 1975.

    Google Scholar 

  62. Sullivan, R. J., et al., Air Pollution Aspects of Arsenic and Its Compounds, NAPCA Project, National Tech. Information Service, Springfield, Virginia, 1969.

    Google Scholar 

  63. Fraumeni, J. F., J. National Cancer Institute 55, 1039, 1975.

    Google Scholar 

  64. Stokinger, H. E., Science 174, Page 662, 1971.

    Article  PubMed  CAS  Google Scholar 

  65. Morton, W., et al., Cancer 37, Page 2523, 1976.

    Article  PubMed  CAS  Google Scholar 

  66. Duggan, R.E. and Weatherwax, J. R., Science 157, Page 1006, 1967.

    Article  PubMed  CAS  Google Scholar 

  67. Johnson, R. D. and Manske, D. D., Pesticide Monitor Journal 9 Page 157, 1976.

    CAS  Google Scholar 

  68. Frost, D. V., Feedstuffs 58(14), Page 55, 1976.

    Google Scholar 

  69. Smith, D. C., et al., Pesticide Science 3, Page 207, 1972.

    Article  CAS  Google Scholar 

  70. Harkins, W. D. and Swain, R. E., J. American Chemical Association 30, Page 928, 1908.

    Google Scholar 

  71. Birmingham, D. J. and Key, M. M., Arch. Dermatology 91, Page 457, 1965.

    Article  CAS  Google Scholar 

  72. Borgono, J. M. and Greiber, R., Trace Substances in Environmental Health, V. D. Hemphill, Editor, University Missouri, Columbia, Page 13, 1971.

    Google Scholar 

  73. Yeh, S., National Cancer Institute Monograph 10, Page 81, 1963.

    Google Scholar 

  74. Tseng, W. P., et al., J. National Cancer Institute 40, Page 453, 1968.

    CAS  Google Scholar 

  75. Grimmett, R. E. R., et al., New Zealand J. Science Technology 21(3A), Page 137, 1939.

    Google Scholar 

  76. Lisella, F. S., et al., J. Environmental Health 34, 511, 1972.

    Google Scholar 

  77. Durham, W. F, Residue Reviews 4, Page 33, 1963.

    PubMed  CAS  Google Scholar 

  78. Nelson, W. C., et al., J. Chron. Disease 26, Page 105, 1973.

    Article  CAS  Google Scholar 

  79. Penrose, W. R., CRC Crit. Review Environmental Control 4, Page 465, 1973.

    Article  Google Scholar 

  80. Pelfrene, A., J. Toxicology Environmental Health 1, Page 1003, 1976.

    Article  CAS  Google Scholar 

  81. Samuels, S. and Howarth, C., Arch. Environmental Health 30, Page 423, 1975.

    CAS  Google Scholar 

  82. Wharton, J. C., Before Silent Spring, Princeton University Press, 1974.

    Google Scholar 

  83. Symposium “Feed Additives and Significance of Their Residues in Animal Tissues,” J. Agr. Feed Chm. 11, Page 362, 1963.

    Google Scholar 

  84. Arsenic, EPA 600/1-76-036, National Technology Information Service, Springfield, Virginia, 1976.

    Google Scholar 

  85. Ganther, H. E., Nutrition Notes 11(3), Page 4, 1975.

    Google Scholar 

  86. El-Begiarmi, M., et al., Poultry Science 53, Page 1921, 1974.

    Google Scholar 

  87. Kroes, R., et al., Food Cosmetic Toxicology 12, Page 671, 1974.

    Article  CAS  Google Scholar 

  88. Groves, K., et al., J. Agricultural Research 13, Page 159, 1946.

    Google Scholar 

  89. Zingaro, R. A., Chemica Scripta 8A, Page 51, 1975.

    CAS  Google Scholar 

  90. Schrauzer, G. N., et al., Bioinorganic Chemistry 6, Page 265, 1976.

    Article  PubMed  CAS  Google Scholar 

  91. Schrauzer, G. N., White, D. A. and Schneider, C. J., Bioinorganic Chemistry 7, Page 35, 1977.

    Article  PubMed  CAS  Google Scholar 

  92. Frost, D. V., CRC Critical Review Toxicology 1, Page 467, 1972.

    Article  CAS  Google Scholar 

  93. Schroeder, H. A. and Balassa, J. J., J. Chron. Dis. 19, Page 83, 1966.

    Google Scholar 

  94. Stevens, L. J., et al., Pesticide Monitor Journal 4, Page 145, 1970.

    CAS  Google Scholar 

  95. Tremarne, T. H. and Jacobs, H. D., USDA Tech. Bulletin 781, USGPO, Washington, D. C., 1941.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Nutrition Biochemistry, 17 Rosa Road, Schenectady, New York, 12308, USA

    Douglas V. Frost (Consultant)

Authors
  1. Douglas V. Frost
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of California at San Diego, La Jolla, California, USA

    G. N. Schrauzer

Rights and permissions

Reprints and permissions

Copyright information

© 1978 Plenum Press, New York

About this chapter

Cite this chapter

Frost, D.V. (1978). The Arsenic Problems. In: Schrauzer, G.N. (eds) Inorganic and Nutritional Aspects of Cancer. Advances in Experimental Medicine and Biology, vol 91. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0796-9_18

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-0796-9_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0798-3

  • Online ISBN: 978-1-4684-0796-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation