Abstract
Iron deficiency has been shown to affect a number of systems including the immune system, the gastrointestinal system, the erythron, and the utilization of at least one essential nutrient and perhaps others. A number of studies have indicated that in irondeficient animals and humans there is decreased killing by polymorpholeucocytes (1,2), but phagocytosis may not be altered. Additionally, in iron-deficient humans, it is shown to depress the response of T cells to mitogens.(3)
Supported in part by Grants CA16750 from the National Cancer Institute, and 508 from the Nutrition Foundation, Inc., New York.
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References
Chandra, R. K., Arch. Dis. Child 48, Page 864, 1973.
Arbeter, A., Echeverri, L., Franco, D., et al., Symposium, Fed. Proceedings 30, Page 142, 1971.
Joyson, D. H. M., Jacobs, A., Walker, D. M. and Dolby, A. E., Lancet 2, Page 1058, 1972.
Jacobs, A., British J. Haemat. 16, Page 1, 1969.
Jacobs, A., Gerent. Clin. 13, Page 61, 1971.
Vitale, J. J., “Deficiency Diseases,” in Pathologic Basis of Disease, S. L. Robbins, Editor, Edition 1, W. B. Saunders Company, Philadelphia, pp. 475–508, 1974.
Chanarin, I., Bennett, M., Berry, V. J. Clinical Path. 15, Page 269, 1962.
Vitale, J. J., Restrepo, A., Velez, H., et al., J. Nutrition 88, Page 315, 1966.
Velez, H., Restrepo, A., Vitale, J. J., et al., American J. Clinical Nutrition 19, Page 27, 1966.
Chanarin, T., Rothman, D., Berry, V. British Medical Journal 1, Page 480, 1965.
Rodday, P., Bennett, M. and Vitale, J. J., Blood 48, Page 435, 1976.
Bennett, M., Cudkowicz, G., Foster, R. S., Jr., Metcalf, D. J. Cell Physiology 71, Page 221, 1968.
Rauchwerger, N. M., Gallagher, M. T. and Trentin., J. J., Transplantation 15, Page 610, 1973.
Rodday, P. and Bennett, M., submitted to Transplantation, 1977.
Comas, F. V. and Byrd, B. L., Radiation Research 32, 355, 1967.
Sztanyik, B. L. and Elson, L. A., Haematologia (Budapest) 3, Page 401, 1969.
Editorial: “Immunosuppression and Human Cancer,” British Medicine 31, page 713, 1972.
Rogers, A. E., Cancer Research 35, Page 2469, 1975.
Rogers, A. E. and Newberne, P. M., Nature 246, Page 491, 1973.
Reddy, B. S., Marisawa, T., Vutusich, D., et al., Proceedings Society Experimental Biology 151, Page 237, 1976.
Weisberger, J. A., Cancer 28, Page 60, 1971.
Hellerstein, E. E., Nakamura, M., Vitale, J. J., et al., J. Nutrition 71, Page 339, 1960.
Haenszel, W., Berg, J. W., Segi, M., et al., J. National Cancer Institute 51, Page 1765, 1973.
Wynder, E. L., Cancer Research 35, Page 3388, 1975.
Armstrong, B. and Doll, R., Intern. J. Cancer 15, 617, 1975.
Wilson, R. B., Wideman, D. P. American J. Clinical Nutrition 30, Page 176, 1976.
Reddy, B., Weisburger, J. H. and Wynder, E. L., J. National Cancer Institute 52, Page 567, 1974.
Amine, E. K. and Hegsted, D. M., J. Nutrition 101, 927, 1971.
Folch, M. H., Sherman, D. Y. C., Herskovic, T., et al., Arch. Pathology 87, Page 526, 1969.
Dollman, P. R. and Goodman, J. R., J. Cell Biology 48, Page 79, 1971.
Amine, E. K. and Hegsted, D. M., J. Nutrition 101, Page 1576, 1976.
Newberne, P. M. and Rogers, A. E., J. National Cancer Institute 50, Page 439, 1973.
Newberne, P. M. and Rogers, A. E., Fundamentals in Cancer Prevention, P. N. Magee, et al., Editors, University of Tokyo Press, Tokyo and University Park Press, Baltimore, pp. 15–40, 1976.
Ghitis, J. and Vitale, J. J., Post Graduate Medicine 34, Page 300, 1963.
Foy, H., Kondi, A. and Verjee, Z. H. M., J. Nutrition 102, Page 571, 1972.
Hoppel, C. L. and Tandler, B., J. Nutrition 105, 562, 1975.
Hoppel, C. L. and Tandler, B., J. Nutrition 106, Page 73, 1976.
Tandler, B. and Hoppel, C. L., Experimental Molecular Pathology 21, Page 88, 1974.
Tandler, B., Erlandson, R. A. and Wynder, E. L., American J. Pathology 52, Page 69, 1968.
Abelev, G. I., Perova, S. D., Khramkova, N. I., et al., Transplantation 1, Page 174, 1963.
Silver, H. K., Gold, P., Shuster, J., et al., New England J. Medicine 291, Page 506, 1974.
Silver, H. K., Gold, P., Shuster, et al., Clinical Research 21, Page 525, 1973.
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Vitale, J.J., Broitman, S.A., Vavrousek-Jakuba, E., Rodday, P.W., Gottlieb, L.S. (1978). The Effects of Iron Deficiency and the Quality and Quantity of Fat on Chemically Induced Cancer. In: Schrauzer, G.N. (eds) Inorganic and Nutritional Aspects of Cancer. Advances in Experimental Medicine and Biology, vol 91. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0796-9_16
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DOI: https://doi.org/10.1007/978-1-4684-0796-9_16
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