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A Comparison of the Effect of Lithium Aid Haloperidol on Human Peripheral β-Adrenergic Adenylate Cyclase

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The Impact of Biology on Modern Psychiatry

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Abstract

Lithium (Li) is an effective therapy in the treatment and prevention of the manic phase of manic-depressive illness (1). Lithium influences a number of physiological systems including biogenic amines (2,3), membrane transport (4–6), amino acid metabolism (7,8) protein synthesis (9–11), endocrine secretion (12) and some kinds of behaviour (13–15). Although the involvement of Li in cellular processes appears to be ubiquitous, no specific mechanism has been identified for Li’s therapeutic efficacy in manic-depressive illness.

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Author information

Authors and Affiliations

  1. The Jerusalem Mental Health Center, P.O.B. 140, Jerusalem, Israel

    Richard P. Ebstein & Robert H. Belmaker

Authors
  1. Richard P. Ebstein
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  2. Robert H. Belmaker
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Editor information

Editors and Affiliations

  1. National Institute of Mental Health, Bethesda, Maryland, USA

    Elliot S. Gershon M.D.

  2. Jerusalem Mental Health Center Ezrath Nashim, Jerusalem, Israel

    Robert H. Belmaker M. D.  & Milton Rosenbaum M. D.  & 

  3. Harvard Medical School, Boston, Massachusetts, USA

    Seymour S. Kety M. D.

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© 1977 Plenum Press, New York

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Ebstein, R.P., Belmaker, R.H. (1977). A Comparison of the Effect of Lithium Aid Haloperidol on Human Peripheral β-Adrenergic Adenylate Cyclase. In: Gershon, E.S., Belmaker, R.H., Kety, S.S., Rosenbaum, M. (eds) The Impact of Biology on Modern Psychiatry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0778-5_2

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  • DOI: https://doi.org/10.1007/978-1-4684-0778-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-0780-8

  • Online ISBN: 978-1-4684-0778-5

  • eBook Packages: Springer Book Archive

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