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Mechanisms of Mediator Release from Inflammatory Cells

  • Chapter
Mediators of Inflammation

Abstract

The inflammatory process is manifested by cell and tissue changes which are in large measure produced by mediating substances derived from various cells or plasma sources. The mediators have the general character that in the normal state they exist as precursors or are sequestered in sites where they are inactive. Stimuli which initiate the inflammatory response then activate or induce synthesis of the mediators or lead to their release. It is this release of mediators from cells which is the subject of this chapter.

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  1. Department of Experimental Pathology, Scripps Clinic and Research Foundation, La Jolla, California, USA

    Peter M. Henson

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  1. Department of Medicine Division of Rheumatology School of Medicine, New York University Medical Center, New York, New York, USA

    Gerald Weissmann

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Henson, P.M. (1974). Mechanisms of Mediator Release from Inflammatory Cells. In: Weissmann, G. (eds) Mediators of Inflammation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-0745-7_2

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  • DOI: https://doi.org/10.1007/978-1-4684-0745-7_2

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