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Infant of the Diabetic Mother

  • Chapter
Principles of Perinatal-Neonatal Metabolism

Abstract

The infant of the diabetic mother (IDM) is a premier example of the problems that may exist in the neonate secondary to maternal disease (diabetes) (Fig. 35.1). (See Chapter 8 for a discussion of diabetes in pregnancy.) From a developmental standpoint the normal neonate is in a transitional state of glucose homeostasis. The fetus is completely dependent on the pregnant female for glucose delivery; and the adult is considered to have precise control of glucose homeostasis, as plasma glucose concentration is regulated to a fine degree.1 In contrast, maintenance of glucose homeostasis may be a major problem even for the normal neonate.2 (See Chapter 20 for a discussion of this concept in the neonate born to the nondiabetic mother.) The precarious nature of this situation is emphasized by the numerous morbidities producing or associated with neonatal hypo- and hyperglycemia during this period. The IDM can be utilized to document not only how far we have come in understanding the pathophysiology of glucose disequilibrium but how far we need to go.

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Authors
  1. Richard M. Cowett
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Editors and Affiliations

  1. Department of Pediatrics, Brown University Program in Medicine, Providence, RI, 02905, USA

    Richard M. Cowett MD (Professor of Pediatrics) (Professor of Pediatrics)

  2. Department of Pediatrics, Women and Infants Hospital of Rhode Island, Providence, RI, 02905, USA

    Richard M. Cowett MD (Professor of Pediatrics) (Professor of Pediatrics)

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© 1991 Springer-Verlag New York Inc.

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Cowett, R.M. (1991). Infant of the Diabetic Mother. In: Cowett, R.M. (eds) Principles of Perinatal-Neonatal Metabolism. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-0400-5_35

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  • DOI: https://doi.org/10.1007/978-1-4684-0400-5_35

  • Publisher Name: Springer, New York, NY

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  • Online ISBN: 978-1-4684-0400-5

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