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Pulmonary Function Tests

  • A. Frans

Abstract

In recent years the number of pulmonary functional tests has increased considerably. For instance, there are no fewer than nine methods to measure the pulmonary diffusing capacity for carbon monoxide (1). However, the clinical usefulness of these tests is quite variable. This chapter shall therefore present the tests in widest use and of greatest value for allergologists,anesthesiologists, epidemiologists, and specialists in internal medicine, pediatrics, and occupational medicine.

Keywords

Lung Volume Forced Vital Capacity Functional Residual Capacity Total Lung Capacity Pulmonary Emphysema 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Frans A: Les Échanges Gazeux Pulmonaires du Sujet Normal et du Mineur de Charbon, thesis. Brussels, 1983Google Scholar
  2. 2.
    Forster RE II, DuBois AB, Briscoe WA, Fisher AB: The Lung ed 3. Chicago, Year Book Medical Publishers, 1986Google Scholar
  3. 3.
    DuBois AB, Botelho SY, Comroe JK: A new method for measuring airway resistance in man using a body plethysmograph. J Clin Invest 35:327–335, 1956PubMedCrossRefGoogle Scholar
  4. 4.
    Harris TR, Pratt PC, Kilburn KH: Total lung capacity measured by roentgenograms. Am J Med 50:756–763 1971PubMedCrossRefGoogle Scholar
  5. 5.
    Loyd HM, String ST, DuBois AB: Radiographic and plethysmographic determinations of total lung capacity. Radiology 86:7–14, 1966PubMedGoogle Scholar
  6. 6.
    Gardner RM, Crapo RO, Teculescu DB: Standardization of spirometry and single breath DLCO tests. Eur Respir J 1:293–296, 1988PubMedGoogle Scholar
  7. 7.
    Chai H, Farr RS, Froehlich LA: Standardization of bronchial inhalation challenge procedures. J Allergy Clin Immunol 56:323–327,1975PubMedCrossRefGoogle Scholar
  8. 8.
    Spector SL, Farr RS: Bronchial inhalation procedures in asthmatics. Med Clin North Am 58:71–84, 1974PubMedGoogle Scholar
  9. 9.
    Guidelines for bronchial inhalation challenges with pharmacologic and antigenic agents. American Thoracic SocietyNews Spring 1980, pp 11–19Google Scholar
  10. 10.
    Weiss EB, Segal MS: Bronchial Asthma. Boxton, Little, Brown & Company, 1976Google Scholar
  11. 11.
    Giffon E, Orehek J, Vervloet D, Arnaud A, Charpin S: Asthma without airway hyperresponsiveness to carbachol. Eur J Respir Dis 70:229–233, 1987PubMedGoogle Scholar
  12. 12.
    Hargreave FE, Ramsdale EH, Pugsley SO: Occupational asthma without bronchial hyperresponsiveness. Am Rev Respir Dis 130:513–515, 1984PubMedGoogle Scholar
  13. 13.
    Stanescu DC, Frans A: Bronchial asthma without increased airway reactivity. Eur J Respir Dis 63:5–12 1982PubMedGoogle Scholar
  14. 14.
    Nadel JA, Tierney DF: Effect of a previous deep inspiration on airway resistance in man. J Appl Physiol 16:717–719,1961PubMedGoogle Scholar
  15. 15.
    Kennedy MCS, Thursby-Pelham DC: Some adrenergic drugs and atropine methonitrate given by inhalation for asthma: A comparative study. Br Med J 1:1018–1021 1964PubMedCrossRefGoogle Scholar
  16. 16.
    Ries AL: Response to bronchodilators, in Clausen JL (ed): Pulmonary Function Testing. Guidelines and Controversies. New York, Grune & Stratton, 1984, pp 215–221Google Scholar
  17. 17.
    Gilbert R, Auchincloss JH, Brodsky J: Changes in tidal volume, frequency and ventilation induced by their measurement. J Appl Physiol 33:252–254, 1972PubMedGoogle Scholar
  18. 18.
    Dolfuss RE, Milic-Emili J, Bates DV: Regional ventilation of the lung studied with boli of xenon133. RespirPhysiol 2:234–246, 1967CrossRefGoogle Scholar
  19. 19.
    McCarthy DS, Spencer R, Greene R, Milic-Emili J: Measurement of closing volume as a simple and sensitive test for early detection of small airway disease. Am J Med 52:747–753,1972PubMedCrossRefGoogle Scholar
  20. 20.
    Grimby G, Takishima T, Graham W, Macklem P, Mead J: Frequency dependance of flow resistance in patients with obstructive lung disease. J Clin Invest 47:1455–1465,1968PubMedCrossRefGoogle Scholar
  21. 21.
    Zarins LP, Clausen JL: Body plethysmography, in Clausen JL (ed): Pulmonary Function Testing. Guidelines and Controversies. New York, Grune & Stratton, 1984, pp 141–153Google Scholar
  22. 22.
    Stanescu DC, Rodenstein D, Cauberghs M, Van De Westijne KP: Failure of body plethysmographic assessment of changes in total lung capacity in asthma. J Appl Physiol: Respirat Environ Exercise Physiol 52:939–948, 1982Google Scholar
  23. 23.
    Pedersen OF, Ingram RH Jr: Configuration of maximum expiratory flow-volume curve: Model experiments with physiological implications. J Appl Physiol 58:1305–1313 1985PubMedGoogle Scholar
  24. 24.
    Brown R, Ingram RH Jr, McFadden ER Jr: Problems in the plethysmographic assessment of changes in total lung capacity in asthma. Am Rev Respir Dis 118:685–692 1978PubMedGoogle Scholar
  25. 25.
    Shore S, Milic-Emili J, Martin JG: Reassessment of body plethysmographic technique for the measurement of thoracic gas volume in asthmatics. Am Rev Respir Dis 126:515–520,1982PubMedGoogle Scholar
  26. 26.
    Hansen LM, Pedersen OF, Lyager N, Naeraa N: Differences in vital capacity due to the methods employed. Ugeskr Laeger 145:2752–2756, 1983PubMedGoogle Scholar
  27. 27.
    Bouhuys A, Hunt VR, Kim BM, Zapletal A: Maximum expiratory flow rates in induced bronchoconstriction in man. J Clin Invest 48: 1159–1168, 1969PubMedCrossRefGoogle Scholar
  28. 28.
    Armitage P: Statistical Methods in Medical Research. Oxford, England, Blackwell Scientific Publications,1971Google Scholar
  29. 29.
    Thiessen B, Pedersen OR: Maximal expiratory flows and forced vital capacity in normal, asthmatic and bronchitic subjects after salbutamol and ipratropium bromide. Respiration 43:304–316, 1982PubMedCrossRefGoogle Scholar
  30. 30.
    Mead J: Analysis of the configuration of maximum expiratory flow volume curves. J Appl Physiol 44:158 165 1978Google Scholar
  31. 31.
    Wagner PD, Dantzker DR, Dueck R, De Polo JL, Wasserman K, West JB: Distribution of ventilationperfusion ratios in patients with interstitial lung disease. Chest 69:256–257, 1976PubMedCrossRefGoogle Scholar
  32. 32.
    Frans A: Measurement of transfer factor for oxygen (TLO2) and carbon monoxide by single-breath method (TLCOsb) Proc R Soc Med 66:35–36, 1973Google Scholar
  33. 33.
    Roughton FJW, Forster RE: Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries. J Appl Physiol 11:290–301, 1957PubMedGoogle Scholar
  34. 34.
    Frans A, Stanescu DC, Veriter C, Clerbaux T, Brasseur L. Smoking and pulmonary diffusing capacity. Scand J Respir Dis 56:165–183, 1975Google Scholar
  35. 35.
    Filley GF, MacIntosh DJ, Wright GW: Carbon monoxide uptake and pulmonary diffusing capacity in normal subjects at rest and during exercise. J Clin Invest 33:530–539, 1954Google Scholar
  36. 36.
    Bates DV, Boucot NG, Dormer AE: The pulmonary diffusing capacity in normal subjects. J Physiol 129:237–252, 1955PubMedGoogle Scholar
  37. 37.
    Kreukniet J, Visser BF: The pulmonary CO diffusing capacity according to Bates and according to Filley in patients with unequal ventilation. Pfiügers Arch 281: 207–211, 1964CrossRefGoogle Scholar
  38. 38.
    Stewart RI: Carbon monoxide diffusing capacity in asthmatic patients with mild airflow limitation. Chest 94:332–336, 1988PubMedCrossRefGoogle Scholar
  39. 39.
    Lewis BM, Lin T-H, Noe FE, Hayford-Welsing EJ: The measurement of pulmonary diffusing capacity for carbon monoxide by a rebreathing method. J Clin Invest 38:2073–2086, 1959PubMedCrossRefGoogle Scholar
  40. 40.
    Nemery B, Piret L, Brasseur L, Frans A: Effect of nitroglycerin on the pulmonary diffusing capacity of normal subjects at rest and during exercise. J Appl Physiol: Respirat Environ Exercise Physiol 52:851–856, 1982Google Scholar
  41. 41.
    West JB: Pulmonary Pathophysiology. The Essentials. Oxford, England, Blackwell Scientific Publications,1977Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • A. Frans

There are no affiliations available

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