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Malignant Pulmonary Disorders

  • P. Stark

Abstract

Metastatic disease results by detachment of malignant cells from a primary tumor and their subsequent arrest and survival in the pulmonary circulation. The process leading to contact of circulating cancer cells with the vascular endothelium is complex and not completely understood. Only a minority of cancer cells invade the blood vessels, survive in the circulation, arrest in small vessels, extravasate into the parenchyma, escape host defense mechanisms, and grow into secondary tumor colonies. These microscopic metastatic foci, not clinically evident at the time of diagnosis, are a major cause of cancer treatment failure(1).

Keywords

Mediastinal Lymph Node Radiation Pneumonitis Bronchogenic Carcinoma Lung Parenchymal Disease Lymphomatoid Granulomatosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • P. Stark

There are no affiliations available

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