Bronchoalveolar and Serum Markers of Lung Disease

  • Yves Sibille
  • William W. Merrill


Although bronchial washings were originally performed with the rigid bronchoscope for various therapeutic purposes, the bronchoalveolar lavage (BAL) technique was developed in the 1970s, shortly after the flexible fiberoptic bronchoscope became widely used (1,2). The sampling of fluid from the lower respiratory tract is now rarely therapeutic. Now such examinations are performed for diagnostic and experimental purposes, providing useful information on both cellular and soluble components of the epithelial lining fluid. The morbidity of the bronchoalveolar lavage is minimal, mostly related to the bronchoscopy procedure, and consists essentially of fever (1 to 2% of cases), easily controlled with antipyretic drugs in most instances. Rarely infection and bleeding occur (3,4).


Alveolar Macrophage Idiopathic Pulmonary Fibrosis Bronchoalveolar Lavage Interstitial Lung Disease Alveolar Space 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • Yves Sibille
  • William W. Merrill

There are no affiliations available

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