Skip to main content
SpringerLink
Log in

Other Tumors

  • Chapter
Tumors and Tumorlike Lesions of Bone and Joints

Abstract

Chordoma is a neoplasm that arises from noto-chordal remnants in the nucleus pulposus of the intervertebral discs, designated as normally situated chordal vestiges and/or from abnormal ectopic remnants, because they are located where notochord should have regressed, i.e., in the spheno-occipital region (including clivai ecchordosis), in the posterior part of nasopharynx, in the substance of bone in the vertebral bodies, or in the tissues surrounding them. Chordoma, therefore, occurs almost exclusively in the midline of the axial skeleton, with a distinct predilection for the distal and proximal ends of the vertebral columna, i.e., the spheno-occipital and sacrococcygeal regions.

Definition, WHO: “A malignant tumor characterized by a lobular arrangement of tissue which is usually made up of highly vacuolated cells (“physaliphorous cells”) and mucoid intercellular material. These tumors are restricted to the axial skeleton.”

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

Chordoma

  • Baker HW, Coley BL (1953) Chordoma of lumbar vertebra. J Bone Joint Surg [Am] 35:403–408

    Google Scholar 

  • Berdal P, Myhre E (1964) Cranial chordomas involving the paranasal sinuses. J Laryngol Otol 78:906–919

    Article  PubMed  CAS  Google Scholar 

  • Congdon CC (1952) Benign and malignant chordomas. A clinico-anatomic study of twenty-two cases. Am JPathol 28:793–821

    CAS  Google Scholar 

  • Crawford T (1958) The staining reactions of chordoma. J Clin Pathol 11:110–113

    Article  PubMed  CAS  Google Scholar 

  • Dahlin DC (1978) Bone tumors, 3rd edn. Thomas, Springfield, Illinois

    Google Scholar 

  • Enzinger F, Shiraki M (1972) Extraskeletal chondro-sarcoma. An analysis of 34 cases. Hum Pathol 3: 421–435

    Article  PubMed  CAS  Google Scholar 

  • Epstein B (1969) The spine. A radiological text and atlas, 3rd edn. Lea & Febiger, Philadelphia

    Google Scholar 

  • Firooznia H, Pinto RS (1977) Chordoma. In: Redigiert von Diethelm L (ed) Encyclopedia of medical radiology, Vol 5, Part 6. Springer-Verlag, Berlin-Heidelberg-New York, pp 354–416 (bibliography)

    Google Scholar 

  • Fox JE, Batsakis JG, Owano LR (1968) Unusual manifestations of chordoma. A report of two cases. J Bone Joint Surg [Am] 50:1618–1628

    CAS  Google Scholar 

  • Friedman I, Harrison DFN, Bird ES (1962) The fine structure of chordoma with particular reference to the physaliferous cell. J Clin Pathol 15:116–125

    Article  Google Scholar 

  • Graf L (1944) Sacrococcygeal chordoma with metastases. Arch Pathol Lab Med 37:136–139

    Google Scholar 

  • Heffelfinger MJ, Dahlin DC, McCarty CS, Beabout JW (1973) Chordomas and cartilaginous tumors at the skull base. Cancer 32:410–420

    Article  PubMed  CAS  Google Scholar 

  • Herndon JH, Cohen J (1970) Chondroma of a lumbar vertebral body resembling a chordoma. J Bone Joint Surg [Am] 52:1241–1247

    CAS  Google Scholar 

  • Higinbotham NL, Philips RF, Farr HW, Hustu HO (1967) Chordoma. iThirty–five-year study at Memorial Hospital. Cancer 20:1841–1850

    Article  PubMed  CAS  Google Scholar 

  • Horowitz T (1941) Chordal ectopia and its possible relation to chordoma. Arch Pathol Lab Med 31: 354–362

    Google Scholar 

  • Husain F (1960) Chordoma of the thoracic spine. J Bone Joint Surg [Br] 42:560

    Google Scholar 

  • Jaffe HL (1958) Tumors and tumorous conditions of the bones and joints. Lea & Febiger, Philadelphia

    Google Scholar 

  • Kamrin RP, Potanos JN, Pool JL (1964) An evaluation of the diagnosis and treatment of chordoma. J Neurol Neurosurg Psychiatry 27:157–165

    Article  PubMed  CAS  Google Scholar 

  • Kay S, Schatzki PF (1972) Ultrastructural observations of a chordoma arising in the clivus. Clinico-pathology reports. Hum Pathol 3:403–413

    Article  PubMed  CAS  Google Scholar 

  • Luschka H (1857) Uber gallertartige Auswüchse am Clivus Blumenbachü. Virchows Arch [Pathol Anat] 11:8

    Google Scholar 

  • Müller H (1858) Über das Vorkommen von Resten der Chorda dorsalis beim Menschen nach der Geburt und über ihr Verhältnis zu den Gallertgeschwülsten am Clivus. Z Rationelle Med 2:202–229

    Google Scholar 

  • Murad TM, Murthy MSN (1970) Ultrastructure of Chordoma. Cancer 25:1204–1215

    Article  PubMed  CAS  Google Scholar 

  • Pearlman AW, Friedman M (1970) Radical radiation therapy of chordoma. Am J Roentgenol, Radium Ther Nucl Med 108:333–341

    Google Scholar 

  • Pena CE, Horvat BL, Fischer ER (1970) The ultra-structure of chordoma. Am J Clin Pathol 53:544–551

    PubMed  CAS  Google Scholar 

  • Ribbert H (1894) Über die Ecchondrosis physalifora spheno-occipitalis. Zentralb Allg. Pathol 5:457–461

    Google Scholar 

  • Schajowicz F, Derqui JC (1968) Puncture biopsy in lesions of the locomotor system. Review of results in 4050 cases, including 941 vertebral punctures. Cancer 21:531–548

    Article  PubMed  CAS  Google Scholar 

  • Schajowicz F, Ackerman LV, Sissons HA (1972) Histological typing of bone tumors. International histological classification of tumors, No. 6. World Health Organization, Geneva

    Google Scholar 

  • Schmorl G (1928) Über Chordareste in den Wirbel-korpern. Zentralbl Chir 55:2305

    Google Scholar 

  • Spjut H, Luse SA (1964) Chordoma. An electron microscopic study. Cancer 17:643–646

    Article  PubMed  CAS  Google Scholar 

  • Stewart MJ, Le F Burrow J (1923) Ecchondrosis physaliphora spheno-occipitalis. J Neurol Psycho-pathol 4:218–220

    Article  CAS  Google Scholar 

  • Stewart MJ, Morin JE (1926) Chordoma: A review with report of a new sacroccygeal case. J Pathol Bacteriol 29:41–60

    Article  Google Scholar 

  • Utne JR, Pugh DG (1955) The roentgenologic aspects of chordoma. Am J Roentgenol, Radium Ther Nucl Med 74:593–608

    CAS  Google Scholar 

  • Wang CC, James AE (1968) Chordoma with a brief review of the literature and report of a case and widespread metastases. Cancer 22:162–167

    Article  PubMed  CAS  Google Scholar 

Adamantinoma of Long Bones

  • Albores Saavedra J, Diaz Gutierrez D, Altamirano Dimas M (1968) Adamantinoma de la tibia. Observaciones ultrastructurales. Rev Med Hosp Gen Mexico City 31:241–252

    Google Scholar 

  • Anderson CE, Saunders JB de CM (1942) Primary adamantinoma of the ulna. Surg Gynecol Obstet 75:351–356

    Google Scholar 

  • Baker PL, Dockerty MB, Coventry MB (1954) Adamantinoma (so-called) of the long bones. Review of the literature and a report of three new cases. J Bone Joint Surg [Am] 36:704–720

    Google Scholar 

  • Bullough PG, Goldenberg VM (1971) Multicentric origin of adamantinoma of the tibia. A case report. Rev Hosp Spec Surg 1:71–74

    Google Scholar 

  • Campanacci M, Giunti A, Leonessa C (1970) Adamantinoma delle ossa lunghe. Chir Organi Mov 58:385–394

    PubMed  CAS  Google Scholar 

  • Changus GW, Speed JS, Stewart FW (1957) Malignant angioblastoma of bone. A reappraisal of adamantinoma of long bone. Cancer 20:540–559

    Article  Google Scholar 

  • Cicero AB (1958) El llamado adamantinoma de los huesos largos. Arch ? Cancer 17:190

    Google Scholar 

  • Cohen DM, Dahlin DC, Pugh DG (1962) Fibrous dysplasia associated with adamantinoma of the long bones. Cancer 15:515–521

    Article  PubMed  CAS  Google Scholar 

  • Dahlin DC (1978) Bone tumors, 3rd edn. Thomas, Springfield, Illinois

    Google Scholar 

  • Diepeveen WP, Hjort GH, Pock-Steen OC (1960) Adamantinoma of the capitate bone. Acta Radiol 53:377–384

    Article  PubMed  CAS  Google Scholar 

  • Elliot GB (1962) Malignant angioblastoma of long bone, so-called “tibial” adamantinoma. J Bone Joint Surg [Br] 44:25–33

    Google Scholar 

  • Etchart M, Viviani G, Behn K (1961) Adamantinom der Ulna. Fortschr Roentgenstr 95:415–418

    Article  PubMed  CAS  Google Scholar 

  • Fischer B (1913) Über ein primares Adamantinom der Tibia. Frank Z Pathol 12:422–441

    Google Scholar 

  • Hicks JD (1954) Synovial sarcoma of the tibia. Pathol Bacteriol 67:151–161

    Article  CAS  Google Scholar 

  • Huvos AG, Marcove RC (1975) Adamantinoma of long bones. A clinico-pathological study of fourteen cases with vascular origin suggested. J Bone Joint Surg [Am] 54:148–154

    Google Scholar 

  • Lauche H (1947) Zur Kenntnis von Pathologie und Klinik der Geschwülste mit synovialmembranartigem Bau (Synovialome, oder synoviale Endothelio-Fibrome und Sarkome). Frankf Z Pathol 59:2–29

    Google Scholar 

  • Lederer H, Sinclair AJ (1954) Malignant synovioma simulating “adamantinoma of the tibia.” J Pathol Bacteriol 67:163–168

    Article  PubMed  CAS  Google Scholar 

  • Lichtenstein L (1977) Bone tumors, 5th edn. Mosby, St Louis, Missouri

    Google Scholar 

  • Llombart-Bosch A, Ortuno-Pacheco G (1978) Ultra-structural findings supporting the angioblastic nature of the so-called adamantinoma of the tibia. Histopathology 2:189–200

    Article  PubMed  CAS  Google Scholar 

  • Maier C (1900) Ein primares myelogenes Platten-Epithelcarcinoma der Ulna. Bruns Beitr Chir 26: 552–566

    Google Scholar 

  • Moon NF (1965) Adamantinoma of the appendicular skeleton. A statistical review of reported cases and inclusion of 10 new cases. Clin Orthop 43:189–213

    PubMed  CAS  Google Scholar 

  • Moon NF (1973) Adamantinoma of the appendicular skeleton. Sound/Slide Program for the American Academy of Orthopedic Surgeons

    Google Scholar 

  • Naji AF, Murphy JA, Stasney RJ, Neville WE, Chrenca P (1964) So-called adamantinoma of long bones. iReport of a case with massive pulmonary metastasis. J Bone Joint Surg [Am] 46:151–158

    CAS  Google Scholar 

  • Robinson HGB (1942) Adamantinoma of the tibia. JAMA 119:1524

    Article  Google Scholar 

  • Rosai J (1969) Adamantinoma of the tibia. Electron microscopic evidence of its epithelial origin. Am J Clin Pathol 51:786–792

    PubMed  CAS  Google Scholar 

  • Ryrie BJ (1932) Adamantinoma of the tibia. Aetiology and pathogenesis. Br Med J 2:1000–1003

    Article  PubMed  CAS  Google Scholar 

  • Schajowicz F, Gallardo H (1967) Adamantinoma de tibia. Rev Ortop Traumatol Lat-Am 12:105–118

    Google Scholar 

  • Schajowicz F, Cabrini RL, Simes RJ (1971) Micro-scopia electronica del “adamantinoma” de los huesos largos. Rev Ortop Traumatol Lat-Am 16:185–194

    Google Scholar 

  • Schajowicz F, Ackerman LV, Sissons HA (1972) Histological typing of bone tumors. International histological classification of tumors, No. 6. World Health Organization, Geneva

    Google Scholar 

  • Spjut HJ, Dorfman HD, Fechner RE, Ackerman LV (1971) Tumors of bone and cartilage. Atlas of tumor pathology, 2nd ser, Fasc 5. Armed Forces Institute of Pathology, Washington, DC

    Google Scholar 

  • Uehlinger EA (1957) Das Skelettsynoviom (Ada-mantinom). In: Roentgendiagnostik, Ergebnisse, 1952–1956. Thieme, Stuttgart, pp 96–103

    Google Scholar 

  • Unni KK, Dahlin DC, Beabout JW, Ivins JC (1974) Adamantinoma of long bones. Cancer 34:1796–1805

    Article  PubMed  CAS  Google Scholar 

  • Weiss SW, Dorfman HD (1977) Adamantinoma of long bones. iAn analysis of nine new cases with emphasis on metastasizing lesions and fibrous dysplasia-like changes. Hum Pathol 8:141–153

    Article  PubMed  CAS  Google Scholar 

  • Yoneyama T, Winter WG, Milsow L (1977) Tibial adamantinoma. Its histogenesis from ultrastructural studies. Cancer 40:1138–1142

    Article  PubMed  CAS  Google Scholar 

  • Zand A, Chamber GH, Street DM (1972) So-called “adamantinoma of long bone.” Clin Orthop 86:178–182

    Article  PubMed  CAS  Google Scholar 

Neurilemmoma and Neurofibroma

  • Aegerter EE (1950) The possible relationship of neurofibromatosis, congenital pseudarthrosis and fibrous dysplasia. J Bone Joint Surg [Am] 32:618–626

    Google Scholar 

  • Baldwin DM, Weiner DS (1974) Congenital bowing and intraosseous neurofibroma of the ulna. A case report. J Bone Joint Surg [Am] 56:803–807

    CAS  Google Scholar 

  • Bose KS, Thakur S, Chakbrarty S, Banerje S (1970) Intraosseous malignant Schwannoma. J Indian Med Assoc 54:328–329

    PubMed  CAS  Google Scholar 

  • Brasfield RO, Das Gupta TK (1972) von Reckling-hausen’s disease—A clinico-pathological study. Ann Surg 175:86–104

    Article  PubMed  CAS  Google Scholar 

  • Cowley AH, Miller DS (1942) Neurilemmoma of bone. A case report. J Bone Joint Surg 24:684–689

    Google Scholar 

  • Del Rio Hortega PD (1962) Tumors of the peripheral nerves. Thomas, Springfield, Illinois de Santos DA, Burgess E (1940) Primary and secondary neurilemmoma of bone. Surg Gynecol Obstet 71:454–461

    Google Scholar 

  • Dickson JH, Waltz TA, Fechner RE (1971) Intraosseous neurilemmoma of the Third Lumbar Vertebra. J Bone Joint Surg [Am] 53:349–355

    CAS  Google Scholar 

  • Fawcett KJ, Dahlin DC (1967) Neurilemmoma of bone. Am J Clin Pathol 47:759–766

    PubMed  CAS  Google Scholar 

  • Fischer ER, Vuzevski VC (1968) Cytogenesis of Schwannoma (neurilemmoma), neurofibroma, dermatofibroma, and dermatofibrosarcoma as revealed by electron microscopy. Am J Clin Pathol 49:141–154

    Google Scholar 

  • Gross P, Bailey FR, Jacox HW (1939) Primary intra-medullary neurofibroma of the humerus. Arch Pathol 28:716–718

    Google Scholar 

  • Giithert H (1952) Ein malignes Neurinom des Knochens. Zentralbl Allg Pathol 88:185

    Google Scholar 

  • Hart MS, Basom WC (1958) Neurilemmoma involving bone. J Bone Joint Surg [Am] 40:465–468

    Google Scholar 

  • Hunt JC, Pugh DG (1961) Skeletal lesions in neurofibromatosis. Radiology 76:1

    PubMed  CAS  Google Scholar 

  • Lewis HH, Korbin HT (1972) Neurilemmoma of the first metacarpal. A case report. Clin Orthop 82:67–69

    PubMed  CAS  Google Scholar 

  • Mazingarbe A, Mazabraud A (1970) A case of neuri-noma of the tibia. Rev Chir Orthop 56:83–88

    PubMed  CAS  Google Scholar 

  • Peers JH (1934) Primary intramedullary neurogenic sarcoma of ulna. Am J Pathol 10:811

    PubMed  CAS  Google Scholar 

  • Polak M (1966) Blastomas del sistema nervioso central y periférico. Lopez, Buenos Aires

    Google Scholar 

  • Prescott GH, White RE (1970) Solitary central neurofibroma of the mandible. Report of a case and review of the literature. J Oral Surg 28:305–309

    PubMed  CAS  Google Scholar 

  • Russell DS, Rubinstein LJ (1963) Tumors of the nerve roots and peripheral nerves. Pathology of tumors of the nervous system, 2nd edn. Williams & Wilkins, Baltimore, Maryland

    Google Scholar 

  • Samter TG, Vellios F, Shafer WG (1960) Neurilemmoma of bone. iReport of 3 cases with a review of the literature. Radiology 75:215–222

    PubMed  CAS  Google Scholar 

  • Sane S, Yonis R (1971) Subperiosteal or cortical cyst and intramedullary neurofibromatosis. Uncommon manifestations of neurofibromatosis. J Bone Joint Surg [Am] 53:1194–1201

    CAS  Google Scholar 

  • Sherman MS (1963) The nerves of bone. J Bone Joint Surg [Am] 45:522–528

    Google Scholar 

  • Waggener JD (1966) Ultrastructure of benign peripheral nerve sheath tumors. Cancer 19:699–709

    Article  PubMed  CAS  Google Scholar 

  • Wilber MC, Woodcock JA (1957) Ganglioneuromata in bone. Report of a case. J Bone Joint Surg [Am] 39:1385

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National University of Buenos Aires, Argentina

    Fritz Schajowicz M.D. (Professor of Pathology, Director, Head, Visiting Distinguished Professor)

  2. International Reference Center for Histo-Pathologic Diagnosis of Bone Tumors and Allied Diseases, World Health Organization and Latin American Registry of Bone Pathology, Argentina

    Fritz Schajowicz M.D. (Professor of Pathology, Director, Head, Visiting Distinguished Professor)

  3. Rush-Presbyterian-St. Luke’s Medical Center, Chicago, Illinois, USA

    Fritz Schajowicz M.D. (Professor of Pathology, Director, Head, Visiting Distinguished Professor)

  4. Osteo-Articular Pathology Center, Hospital Italiano, Gascon 450, Buenos Aires, Argentina

    Fritz Schajowicz M.D. (Professor of Pathology, Director, Head, Visiting Distinguished Professor)

Authors
  1. Fritz Schajowicz M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Springer-Verlag New York Inc.

About this chapter

Cite this chapter

Schajowicz, F. (1981). Other Tumors. In: Tumors and Tumorlike Lesions of Bone and Joints. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-0098-4_8

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-0098-4_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-0100-4

  • Online ISBN: 978-1-4684-0098-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation