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Epidemiology and Natural History of Phenylketonuria and Other Hyperphenylalaninemias

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Dietary Phenylalanine and Brain Function

Abstract

Millions of newborn infants all over the world are screened today for phenylketonuria (PKU), and many thousands of early-treated children and young persons are bright and completely normal. Research workers from many disciplines have cooperated to elucidate the biochemical and genetic background of PKU and other hyperphenylalaninemias and to prevent these inherited metabolic errors before clinical symptoms appear. This is a brief summary of the history of hyperphenyl-alaninemia covering a period of five decades from the time of Følling’s first publication in 1934.

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  1. The John F. Kennedy Institute, DK-2600 Glostrup, Copenhagen, Denmark

    Flemming Güttler

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  1. Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA

    Richard J. Wurtman M.D.  & Eva Ritter-Walker  & 

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© 1988 Birkhäuser Boston

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Güttler, F. (1988). Epidemiology and Natural History of Phenylketonuria and Other Hyperphenylalaninemias. In: Wurtman, R.J., Ritter-Walker, E. (eds) Dietary Phenylalanine and Brain Function. Birkhäuser Boston. https://doi.org/10.1007/978-1-4615-9821-3_26

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  • DOI: https://doi.org/10.1007/978-1-4615-9821-3_26

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4615-9823-7

  • Online ISBN: 978-1-4615-9821-3

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