Abstract
Gestational diabetes mellitus (GDM) affects placental composition and intrinsic metabolism both in humans (1) and rats (2), and causes abnormalities in maternal-fetal metabolite tranfer (3). These changes may actively contribute to the altered fetal growth that occurs in GDM, which directly depends on the quality and quantity of metabolic fuels crossing the placenta. These fuels may be used as building blocks for fetal accretion and also modulate fetal beta-cell insulin release which is recognized as an important growth factor for the fetus (4).
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© 1990 Plenum Press, New York
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Martín, A., Palacín, M., Lasunción, M.A., Herrera, E. (1990). Fetal/Maternal Plasma Amino Acid Relationships in the Streptozotocin Diabetic Rat. In: Cuezva, J.M., Pascual-Leone, A.M., Patel, M.S. (eds) Endocrine and Biochemical Development of the Fetus and Neonate. Reproductive Biology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9567-0_29
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DOI: https://doi.org/10.1007/978-1-4615-9567-0_29
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