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Methotrexate Influences Peritoneal Permeability

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Book cover Ambulatory Peritoneal Dialysis

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Abstract

Intraperitoneal application of antineoplastic drugs is neither a standard nor a widely used procedure in oncological therapy. However, some trials of this arrangement have been undertaken in clinical practice.(1–3) These drugs can induce damage to peritoneum causing a change in the diffusibility of this membrane. In order to check this side effect of cytostatics, series of experiments on isolated rabbit parietal peritoneum were performed, in which the influence of methotrexate (MTX) on the permeability of the membrane in vitro was measured.

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References

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Authors
  1. K. Czyżewska
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  2. C. Ramlau
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  3. J. Knapowski
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Editor information

Editors and Affiliations

  1. The Long Island College Hospital, SUNY-Health Science Center at Brooklyn, Brooklyn, New York, USA

    Morrell M. Avram M.D., F.A.C.P. , Neal Mittman M.D. , Paul A. Fein M.D. , Amado Gan M.D. , Philip Goldwasser M.D.  & Paul A. Slater M.D. , , , ,  & 

  2. Instituto Di Medicina Interna E. Nefrologia, Universita Degli Studi di Napoli, Napoli, Italy

    Carmelo Giordano M.D.

  3. Prima Facolta di Medicina Universita, Napoli, Italy

    Natale G. DeSanto M.D. (Cattedra di Nefrologia Pediatrica) (Cattedra di Nefrologia Pediatrica)

  4. Servizio di Nefrologia ed Emodialisi Umberto I, Mestre, Venice, Italy

    Giorgio Bazzato

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© 1990 Plenum Publishing Corporation

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Czyżewska, K., Ramlau, C., Knapowski, J. (1990). Methotrexate Influences Peritoneal Permeability. In: Avram, M.M., et al. Ambulatory Peritoneal Dialysis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9555-7_23

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  • DOI: https://doi.org/10.1007/978-1-4615-9555-7_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9557-1

  • Online ISBN: 978-1-4615-9555-7

  • eBook Packages: Springer Book Archive

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