Abstract
The primate corpus luteum of the menstrual cycle secretes progesterone for 14–16 days after ovulation in the absence of an implanted conceptus (1). In fertile cycles, the luteal life span is prolonged by the secretion of chorionic gonadotropin by the trophoblast (2). In view of its absolute requirement for implantation and early gestation, specific knowledge of the regulation of the corpus luteum is important for effective control of fertility as well as correcting the pathophysiological conditions of short and inadequate luteal phases.
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References
Knobil E. On the regulation of the primate corpus luteum. Biol Reprod 1973; 8:246–58.
Atkinson LE, Hotchkiss J, Fritz GR, Surve AH, Neill JD, Knobil E. Circulating levels of steroids and chorionic gonadotropin during pregnancy in the rhesus monkey with special attention to the rescue of the corpus luteum in early pregnancy. Biol Reprod 1975; 12:335–45.
Cameron JL, Stouffer RL. Gonadotropin receptors of the primate corpus luteum. I. Characterization of 125I-labeled human luteinizing hormone and human chorionic gonadotropin binding to luteal membranes from the rhesus monkey. Endocrinology 1982; 110:2059–67.
Eyster KM, Stouffer RL. Adenylate cyclase in the corpus luteum of rhesus monkeys. I. General properties and optimal assay conditions. Endocrinology 1985; 116:1543–51.
Van de Wiele RL, Bogumil J, Dryenfurth I, et al. Mechanisms regulating the menstrual cycle in women. Recent Prog Horm Res 1970; 26:63–87.
Mougdal NR, MacDonald GJ, Greep RO. Role of endogenous LH in maintaining corpus luteum function of the monkey. J Clin Endocrinol Metab 1972; 35:113–6.
Asch RH, Moustapha AS, Braunstein GD, Pauerstein CJ. Luteal function in hypophysectomized rhesus monkeys. J Clin Endocrinol Metab 1982; 55:154–61.
Knobil E, Plant TM, Wildt L, Belchetz PE, Marshall G. Control of the rhesus monkey menstrual cycle: permissive role of gonadotropin releasing hormone. Science 1980; 207:1371–3.
Plant TM, Krey LC, Moosey J, McCormack JT, Hess DL, Knobil E. The arcuate nucleus and the control of gonadotropin and prolactin secretion in the female rhesus monkey. Endocrinology 1978; 102:52–62.
Carmel PW, Araki S, Ferin M. Pituitary stalk portal blood collection in rhesus monkeys: evidence for pulsatile release of gonadotropin releasing hormone. Endocrinology; 99:243–8.
Hutchison JS, Zeleznik AJ. The rhesus monkey corpus luteum is dependent in pituitary gonadotropin secretion throughout the luteal phase of the menstrual cycle. Endocrinology 1984; 115:1780–6.
Hutchison JS, Zeleznik AJ. The corpus luteum of the primate menstrual cycle is capable of recovering from a transient withdrawal of pituitary gonadotropin support. Endocrinology 1985; 117:1043–9.
Filicori M, Butler JP, Crowley WF Jr. Neuroendocrine regulation of the corpus luteum in the human. J Clin Invest 1984; 73:1638–47.
Ellinwood WE, Normal RL, Spies HG. Changing frequency of pulsatile luteinizing hormone and progesterone secretion during the luteal phase of the menstrual cycle of rhesus monkeys. Biol Reprod 1984; 31:714–22.
Hutchison JS, Zeleznik AJ. Effects of different gonadotropin pulse frequencies on corpus luteum function during the menstrual cycle of rhesus monkeys. Endocrinology 1986; 119:1964–71.
Karsch FJ, Krey LC, Weick RF, Dierschke DJ, Knobil E. Functional luteolysis in the rhesus monkey: the role of estrogen. Endocrinology 1973; 92:1148–52.
Gore BZ, Caldwell BU, Speroff L. Estrogen induced human luteolysis. J Clin Endocrinol Metab 1973; 36:615–7.
Hotchkiss J, Atkinson LE, Knobil E. Time course of serum estrogen and luteinizing hormone concentration during the menstrual cycle of the rhesus monkey. Endocrinology 1971; 89:177–83.
Butler WR, Hotchkiss J, Knobil E. Functional luteolysis in the rhesus monkey: ovarian estrogen and progesterone during the luteal phase of the menstrual cycle. Endocrinology 1975; 96:1509–12.
Ellinwood WE, Resko JA. Effect of inhibition of estrogen synthesis during the luteal phase on function of the corpus luteum in rhesus monkeys. Biol Reprod 1983; 28:636–44.
Albrecht ED, Haskins AL, Hodgen GD, Pepe GJ. Luteal function in baboons with administration of the antiestrogen ethamoxytiphetol (MER-25) throughout the luteal phase of the menstrual cycle. Biol Reprod 1981; 25:451–7.
Westfahl PK, Resko JA. The affects of clomiphene in luteal function in the nonpregnant cynomolgus macaque. Biol Reprod 1983; 29:963–9.
Karsch FJ, Sutton GP. An intra-ovarian site for the luteolytic action of estrogen in the rhesus monkey. Endocrinology 1976; 98:553–61.
Schoonmaker JN, Bergman KS, Steiner RA, Karsch FJ. Estradiol-induced luteal regression in the rhesus monkey: evidence for an extraovarian site of action. Endocrinology 1982; 110:1708–15.
Hutchison JS, Kubik CJ, Nelson PB, Zeleznik AJ. Estrogen induces premature luteal regression in rhesus monkeys during spontaneous menstrual cycles, but not in cycles driven by exogenous gonadotropin releasing hormone. Endocrinology 1987; 120 (in press).
Ottobre JS, Stouffer RC. Persistent versus transient stimulation of the macaque corpus luteum during prolonged exposure to human chorionic gonadotropin: a function of age of the corpus luteum. Endocrinology 1984; 114:2175–82.
Auletta FJ, Kamps DL, Pories S, Bisset J, Gibson M. An intracorpus luteum site for the luteolytic action of prostaglandin F2α in the rhesus monkey. Prostaglandins 1984; 27:285–98.
Auletta FJ, Paradis DK, Wesley M, Duby RT. Oxytocin is luteolytic in the rhesus monkey (Macaca mulatta). J Reprod Fertil 1984; 72:406.
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© 1987 Plenum Press, New York
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Zeleznik, A.J., Hutchison, J. (1987). Luteotropic Actions of LH on the Macaque Corpus Luteum. In: Stouffer, R.L. (eds) The Primate Ovary. Serono Symposia, USA. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9513-7_11
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DOI: https://doi.org/10.1007/978-1-4615-9513-7_11
Publisher Name: Springer, Boston, MA
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