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Perspectives on Ovarian Stimulation and in Vitro Fertilization in Primate Models

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Abstract

Since the inception of in vitro fertilization and embryo transfer (IVF/ET) therapy by Edwards and Steptoe in the mid-70s, nothing has increased the pregnancy rate of this procedure as dramatically as the decision to employ enhancement of the natural ovarian/menstrual cycle in order to attempt collection of several oocytes from each patient during each treatment cycle. Here, we will review first the underlying physiological mechanisms in the natural ovarian cycle in order to serve us in the second case, where our purpose is to override selection of the dominant follicle to facilitate aspiration of several preovulatory oocytes for IVF/ET therapy (Fig. 1).

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© 1987 Plenum Press, New York

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Hodgen, G.D. (1987). Perspectives on Ovarian Stimulation and in Vitro Fertilization in Primate Models. In: Stouffer, R.L. (eds) The Primate Ovary. Serono Symposia, USA. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9513-7_10

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  • DOI: https://doi.org/10.1007/978-1-4615-9513-7_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9515-1

  • Online ISBN: 978-1-4615-9513-7

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