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Vascular Smooth Muscle: Structure and Function

  • Chapter
Central and Peripheral Mechanisms of Cardiovascular Regulation

Part of the book series: NATO ASI Series ((NSSA,volume 109))

Abstract

The hemodynamic characteristics of the vasculature are determined primarily by the vascular characteristic impedance, flow resistance, and wall stiffness. The first is of most importance in the larger Windkessel vessels and determines the pulse pressure for a given oscillatory flow. The second concerns primarily the vessels responsible for flow distribution (the small arteries and arterioles) and gives the steady flow maintained by a given perfusion pressure. The third is of importance as regards the capacitance vessels (the small veins) as well as the vessels which determine the venous return pressure (the large veins) and gives the change in transmural pressure for a given change in vascular volume. These characteristics are functions of the vessel caliber and the elastic modulus of the vascular wall (McDonald, 1974; Dobrin, 1978; Caro et al., 1978; Gow, 1980; Mulvany, 1984b).

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  1. Biophysics Institute, Aarhus University, 8000, Aarhus C., Denmark

    Michael J. Mulvany

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  1. Michael J. Mulvany
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  1. Wadsworth Center for Laboratories and Research, Albany, New York, USA

    A. Magro

  2. University of Porto, Porto, Portugal

    W. Osswald

  3. Cornell University Medical College, New York, New York, USA

    D. Reis

  4. Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

    P. Vanhoutte

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Mulvany, M.J. (1986). Vascular Smooth Muscle: Structure and Function. In: Magro, A., Osswald, W., Reis, D., Vanhoutte, P. (eds) Central and Peripheral Mechanisms of Cardiovascular Regulation. NATO ASI Series, vol 109. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9471-0_4

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  • DOI: https://doi.org/10.1007/978-1-4615-9471-0_4

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