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Endothelium as a Modulator of Platelet Reactivity

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Book cover Mechanisms of Stimulus—Response Coupling in Platelets

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 192))

Abstract

Endothelium can modulate platelet reactivity directly by affecting platelet adhesion, aggregation and secretion; platelet reactivity can also be modulated indirectly by controlling vascular tone (and hence blood flow) and the activation of the coagulation system. In this review, the activities of endothelial cells that modulate these various processes will be briefly summarised.

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Author information

Authors and Affiliations

  1. Vascular Biology Section, MRC Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ, UK

    J. L. Gordon

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  1. J. L. Gordon
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Royal College of Surgeons, London, England

    J. Westwick

  2. Thrombosis Research Unit, King’s College School of Medicine and Dentistry, London, England

    M. F. Scully  & V. V. Kakkar  & 

  3. Department of Pharmacology, University of Glasgow, Glasgow, Scotland

    D. E. MacIntyre

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© 1985 Plenum Press, New York

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Gordon, J.L. (1985). Endothelium as a Modulator of Platelet Reactivity. In: Westwick, J., Scully, M.F., MacIntyre, D.E., Kakkar, V.V. (eds) Mechanisms of Stimulus—Response Coupling in Platelets. Advances in Experimental Medicine and Biology, vol 192. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9442-0_30

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  • DOI: https://doi.org/10.1007/978-1-4615-9442-0_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9444-4

  • Online ISBN: 978-1-4615-9442-0

  • eBook Packages: Springer Book Archive

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