Oral Viral Leukoplakia — A New AIDS-Associated Condition

  • John S. Greenspan
  • Deborah Greenspan
  • Evelyne T. Lennette
  • Donald I. Abrams
  • Marcus A. Conant
  • Vibeke H. Petersen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 187)


Viral leukoplakia of the tongue in immunosuppressed male homosexuals (oral “hairy” leukoplakia, H.L.) is a newly described lesion showing an association with the subsequent development of AIDS, often with Pneumocystis carinii pneumonia. The lesion appears to contain papillomavirus as well as a second virus of the herpes-group (1). In this paper we present evidence for the presence, within the epithelial cells of hairy leukoplakia, of both papillomavirus and Epstein-Barr virus (EBV), and for the presence of EB viral capsid antigen (VCA).


Nasopharyngeal Carcinoma Lichen Planus Infectious Mononucleosis Viral Capsid Antigen Prickle Cell 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • John S. Greenspan
    • 1
  • Deborah Greenspan
    • 1
  • Evelyne T. Lennette
    • 1
  • Donald I. Abrams
    • 1
  • Marcus A. Conant
    • 1
  • Vibeke H. Petersen
    • 1
  1. 1.Schools of Dentistry and Medicine and AIDS Clinical Research CenterUniversity of California San Francisco and Virolab EmeryvilleUSA

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