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Clinical and Biological Aspects of Essential Thrombocythemia

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Advances in Hemostasis and Thrombosis

Part of the book series: Ettore Majorana International Science Series ((LIFESCI,volume 20))

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Abstract

Essential thrombocythemia (ET) is a clonal myeloproliferative disease that involves a multipotent stem cell common to the megakaryocyte, granulocytic, and erythrocytic lines (16). In ET the major abnormality is represented by the increase of the megakaryocyte number, volume, and mass (13,25,26,45). The resulting platelet production is usually 4–6 times more than the normal value, while the platelet survival is normal or slightly decreased (25,29,34,43,45).

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Author information

Authors and Affiliations

  1. Essential Thrombocythemia Italian Study Group, Institute of Hematology, University of Bologna, Bologna, Italy

    S. Tura, L. Gugliotta, M. Baccarani, C. Bernasconi, C. Biagini, P. Boccaccio, A. Canevari, G. Cavazzini, L. Chetti, A. Grossi, A. Guarini, G. Isacchi, F. Mandelli, P. M. Mannucci, M. Morfini, F. I. Pareti, P. Ricci, D. Russo, P. L. Rossi Ferrini, E. Salvidio & A. Zaccaria

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Editors and Affiliations

  1. University of Palermo, Palermo, Italy

    A. Cajozzo , R. Perricone , P. Di Marco  & P. Palazzolo , ,  & 

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© 1985 Plenum Press, New York

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Tura, S. et al. (1985). Clinical and Biological Aspects of Essential Thrombocythemia. In: Cajozzo, A., Perricone, R., Di Marco, P., Palazzolo, P. (eds) Advances in Hemostasis and Thrombosis. Ettore Majorana International Science Series, vol 20. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9424-6_25

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  • DOI: https://doi.org/10.1007/978-1-4615-9424-6_25

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