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Microtubules in Vertebrate Photoreceptors

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Photoreceptors

Part of the book series: NATO Asi Series ((NSSA,volume 75))

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Abstract

Microtubules (MTs) are now recognised as being ubiquitous in eucaryotic cells. On the basis of their varied and wide occurrence, as well as the mode of action of specific inhibitors (e.g. colchicine, Vinca alkaloids) on cellular activies MTs, despite their simple and uniform structure, are postulated to have several functions. These include: direct or indirect participation in cell motility; intracellular transport of cytoplasmic particules or substances; and the formation and maintenance of asymmetrical cell shape as a sort of cytoskeleton. It is possible that the cytoplasmic MTs in retinas may participate in each of the above functions. Since many excellent reviews have appeared recently on the subject of MTs (Dustin, 1978; Gaskin & Shelanski, 1976; Goldman et al., 1976; Olmsted & Borisy, 1973; Roberts & Hyams, 1979; Sakai, 1980; Soifer, 1975; Stephens, 1975; Wilson & Bryan, 1974) only the essentials of MT structure and biochemistry required to understand the functions of the cytoplasmic MTs of the retina will be discussed in this chapter.

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  1. Département de Biologie, Université de Montréal, Canada

    M. A. Ali & M. A. Klyne

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  1. University of Genova, Genova, Italy

    A. Borsellino

  2. Institute of Neurophysiology of the CNR, Pisa, Italy

    L. Cervetto

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Ali, M.A., Klyne, M.A. (1984). Microtubules in Vertebrate Photoreceptors. In: Borsellino, A., Cervetto, L. (eds) Photoreceptors. NATO Asi Series, vol 75. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9382-9_15

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