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Production of Gamma (Immune) Interferon by a Permanent Human T-Lymphocyte Cell Line

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Eukaryotic Cell Cultures

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 172))

Abstract

Gamma (immune, type II) interferon is an antiviral and immunoregulatory glycoprotein usually obtained from mitogen- or antigeninduced peripheral blood or splenic mononuclear cells. A human “helper-inducer” T-lymphocyte cell line (Mo) is an inducible source of gamma interferon. Mo gamma interferon has been biochem ically characterized and partially purified, and resembles the gamma interferon species derived from normal cell sources.

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© 1984 Plenum Press, New York

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Groopman, J.E., Nathan, I., Golde, D.W. (1984). Production of Gamma (Immune) Interferon by a Permanent Human T-Lymphocyte Cell Line. In: Acton, R.T., Daniel Lynn, J. (eds) Eukaryotic Cell Cultures. Advances in Experimental Medicine and Biology, vol 172. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9376-8_13

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  • DOI: https://doi.org/10.1007/978-1-4615-9376-8_13

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