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Contribution of Monoclonal Anti-T Cell Antibody in the Follow-Up and the Immunosuppressive Treatment of Renal Transplant Patients

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Abstract

Over the past few years considerable insight has been gained on the humoral and cellular immune reactions triggered by an allotransplanted organ. However, from a practical point of view, the immunological monitoring of patients receiving a renal allograft still remains an elusive and finally unsolved matter. By now, no simple immunological test has been described that correlates in a reliable fashion with the clinical evolution of the graft. In the particular case of renal transplantation, the situation is further complicated by the nearly exclusive use of serum creatinine to define graft rejection. In fact, creatininemia only increases when advance renal damage has occurred and is not always due to a rejection process.

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© 1984 Plenum Press, New York

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Chatenoud, L., Baudrihaye, M., Chkoff, N., Kreis, H., Bach, JF. (1984). Contribution of Monoclonal Anti-T Cell Antibody in the Follow-Up and the Immunosuppressive Treatment of Renal Transplant Patients. In: Fudenberg, H.H., Whitten, H.D., Ambrogi, F. (eds) Immunomodulation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9358-4_28

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  • DOI: https://doi.org/10.1007/978-1-4615-9358-4_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9360-7

  • Online ISBN: 978-1-4615-9358-4

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