Abstract
The benefits of using enzyme-dependent procedures for overcoming difficult organic synthetic problems has been recognized for many years. This is illustrated by the extensive use of microbiological fermentation methods (1) and the increasing applications of immobilized enzymes and cells (2). In spite of this substantial documentation, enzymic methods have not yet been widely accepted by organic chemists as routine catalysts. However, this situation is changing rapidly; and the most recent literature shows clearly that the aware organic chemist now recognizes the unique synthetic advantages that enzymes offer.
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References
Kieslich, K. “Microbial Transformations of Non-Steroid Cyclic Compounds”, Thieme, Stuttgart (1976).
Mosbach, K. Meth. Enzymol. 44: (1976).
“Enzyme Nomenclature”, Elsevier, New York (1973).
Baricos, W. H., Chambers, R. P., & Cohen, W. Anal. Lett. 9: 257 (1976).
Jones, J. B. & Beck, J. F. Tech. Chem. (N.Y.) 10: JONES, J. B. in “Enzymic and Non Enzymic Catalysis” (P. Dunnill, A. Wiseman, and N. Blakeborough, eds.) E. Horwood/J. Wiley, Chichester/New York (1980) p. 54.
Baughn, R. L. , Adalsteinsson, O. , & Whitesides, G. M. J. Amer. Chem. Soc. 100: 304 (1978).
Wong, C-H. & Whitesides, G. M. J. Amer. Chem. Soc. 103: 4890 (1981).
Johnson, S. C. & Tauzon, P. T. Biochemistry 16.
Oppenheimer, N. J. & Kaplan, N. 0. Biochemistry 13: (1974).
Zagalak, B. , Frey, P. A., Karabatsos, G. L. , & Abeles, R. H. J. Biol. Chem. 241: 3028 (1966).
Jones, J. B., & Taylor, K. E. Can. J. Chem. 55: s(1976).
Eliel, E. L. J. Chem. Ed. 57: 52 (1980).
Jones, J. B.Tech. Chem. N.Y. 10: 479 (1976).
Prelog, V. Pure Appi. Chem. 9: 119 (1964).
Jones, J. B. & Jakovac, I. J. Can. J. Chem., in press.
Battersby, A. R. , Sheldrake, P. W. , Staunton, J. , & Williams, D. C. J. Chem. Soc. Perkin I1056 (1976).
Cornforth, J. W., Ross, F. P., & Wakselman, C. J. Chem. Soc. Perkin I429 (1975).
Irwin, A. J. & Jones, J. B. J. Amer. Chem. Soc. 98: 8476 (1976); 99: 556, 1625 (1977).
Davies, J. & Jones, J. B. J. Amer. Chem. Soc. 101: 5405 (1979).
Goodbrand, H. B. & Jones, J. B.Ch&n. Commun. 469 (1977).
Jakovac, I. J., Ng, G., Lok, K. P., & Jones, J. B. Chem. Commun. 515 (1980).
Jones, J. B. & Dodds, D., unpublished results.
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© 1982 Plenum Press, New York
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Jones, J.B. (1982). Horse Liver Alcohol Dehydrogenase: An Illustrative Example of the Potential of Enzymes in Organic Synthesis. In: Chibata, I., Fukui, S., Wingard, L.B. (eds) Enzyme Engineering. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9290-7_12
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DOI: https://doi.org/10.1007/978-1-4615-9290-7_12
Publisher Name: Springer, Boston, MA
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