Abstract
The honeycomb structure which has been reported to exist in cervical mucus (Chretien et al., 1973) and intestinal goblet cell mucus (Forstner et al., 1977) has been investigated by Parish et al. (1981), who showed the apparent structure to be an artefact resulting from ice crystal formation during the freezing stage of sample preparation for examination in the scanning electron microscope (SEM). The artefact is modified by differences in water content of the gel and freezing rate of the sample. We report here the effects of alterations in the viscosity of the mucin gel, produced by a variety of low molecular weight substances.
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References
D. T. Brown, C. Marriott and M. F. Beeson, 1981, A Rheological study of mucus-antibiotic interactions, this publication.
F. C. Chretien, C. Gernigon, G. David and A. Psychoyos, 1973, The ultrastructure of human cervical mucus under scanning electron microscopy, Fertility and Sterility, 24: 746.
G. Forstner, J. Sturgess and J. Forstner, 1977, Malfunction of intestinal mucus and mucus production, in: Mucus in Health and Disease, M. Elstein and D. V. Parke, eds., Plenum Publishing Corporation, N.Y.
C. Marriott, C. K. Shih and M. Litt, 1979, Changes in the gel properties of tracheal mucus induced by divalent cations, Biorheology, 16: 331.
C. Marriott, D. T. Brown and M. F. Beeson, 1981, Evaluation of mucolytic activity using a purified mucus glycoprotein gel, this publication.
G. R. Parish, M. F. Beeson, D. T. Brown and C. Marriott, 1981, A freezing artefact associated with the preparation of mucin for examination using the scanning electron microscope, this publication.
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© 1982 Plenum Press, New York
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Beeson, M.F., Parish, G.R., Brown, D.T., Marriott, C. (1982). The Effects of Low Molecular Weight Mucus Modifying Substances on the Appearance of Mucin Gels in the Scanning Electron Microscope. In: Chantler, E.N., Elder, J.B., Elstein, M. (eds) Mucus in Health and Disease—II. Advances in Experimental Medicine and Biology, vol 144. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9254-9_58
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DOI: https://doi.org/10.1007/978-1-4615-9254-9_58
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-9256-3
Online ISBN: 978-1-4615-9254-9
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