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Trisaccharides from Blood Group A1 And A2 Mucous Glycoproteins

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Mucus in Health and Disease—II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 144))

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Abstract

The mucous glycoproteins of human origin may possess A, B, H and Lewis blood group activity and the structures of the blood group determinants responsible for these activities have been established (see ref.1). However, the nature of the difference between A1 and A2, the two main subgroups of A, is still unclear. One theory states that there are structural differences between the determinants in A1 and A2 materials, and Moreno et al2 have suggested that the existence of two types of A-determinant might form the basis for such structural differences. They proposed that A1 materials carry both Type 1 and Type 2 A-determinants whereas only Type 2 A-determinants are present in A2 materials.

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References

  1. W.M. Watkins in: “Glycoproteins”, A. Gotschalk, ed., Part B, p 830, Elsevier, Amsterdam (1972)

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© 1982 Plenum Press, New York

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Donald, A.S.R. (1982). Trisaccharides from Blood Group A1 And A2 Mucous Glycoproteins. In: Chantler, E.N., Elder, J.B., Elstein, M. (eds) Mucus in Health and Disease—II. Advances in Experimental Medicine and Biology, vol 144. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9254-9_5

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  • DOI: https://doi.org/10.1007/978-1-4615-9254-9_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9256-3

  • Online ISBN: 978-1-4615-9254-9

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