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Trisaccharides from Blood Group A1 And A2 Mucous Glycoproteins

  • Alastair S. R. Donald
Chapter
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Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 144)

Abstract

The mucous glycoproteins of human origin may possess A, B, H and Lewis blood group activity and the structures of the blood group determinants responsible for these activities have been established (see ref.1). However, the nature of the difference between A1 and A2, the two main subgroups of A, is still unclear. One theory states that there are structural differences between the determinants in A1 and A2 materials, and Moreno et al2 have suggested that the existence of two types of A-determinant might form the basis for such structural differences. They proposed that A1 materials carry both Type 1 and Type 2 A-determinants whereas only Type 2 A-determinants are present in A2 materials.

Keywords

Blood Group Ovarian Cyst Acetic Anhydride Secrete Glycoprotein Mucous Glycoprotein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    W.M. Watkins in: “Glycoproteins”, A. Gotschalk, ed., Part B, p 830, Elsevier, Amsterdam (1972)Google Scholar
  2. 2.
    C. Moreno, A. Lundblad and E.A. Kabat, J. Exp. Med. 134 : 439 (1971)PubMedCrossRefGoogle Scholar
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    W.M. Watkins and W.T.J. Morgan, Acta Genet. Statist. Med. 6 : 521 (1956/57)Google Scholar
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    A.S.R. Donald, J. Chromatogr. 134: 199 (1977)PubMedCrossRefGoogle Scholar
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    S. Takasaki, K. Yamashita and A. Kobata, J. Biol. Chem. 253 : 6086 (1978)PubMedGoogle Scholar
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    R. Oriol, Blood Transfusion and Immunohaematology 23 : 517 (1980)Google Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Alastair S. R. Donald
    • 1
  1. 1.Division of Immunochemical GeneticsMRC Clinical Research CentreHarrowGreat Britain

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