Histochemical Alterations in the Uterine Endocervical Mucosa in Different Phases of the Normal Menstrual Cycle and in the Altered Cycle

  • V. Nirmala
  • John A. Thomas
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 144)


Cervical mucus contributes towards the hostile vaginal environment and interferes with the entry of the spermatozoa into the uterus at all times except during the periovulatory period of the normal menstrual cycle. During this period the normally acidic, thick, viscid cervical mucus becomes less acid, thin and watery. The resultant changes in pH and consistency is believed to protect the spermatozoa from the hostile vaginal environment and also help in sperm transport. (Elstein, 1978; Kroeks, Kremer, 1977; Moghissi, 1973).


Endometrial Carcinoma Normal Cycle Cervical Mucus Normal Menstrual Cycle Acid Mucin 
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  1. Elstein, M., 1978. Functions and physical properties of mucus in the female genital tract. Br. Med. Bull. 34, 83–88.PubMedGoogle Scholar
  2. Kroeks, M.V.A.M. and Kremer, J., 1977. The pH in the lower third of the genital tract. IN: The Uterine cervix in Reproduction. Ed. V. Insler and G. Buttendorf Georg Thieme Publishers, Stuttgart.Google Scholar
  3. Moghissi, K.S., 1973. IN: Cervical mucus in human reproduction. M. Elstein; K.S. Moghissi, R. Borth., Scriptor., Copenhagen.Google Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • V. Nirmala
    • 1
  • John A. Thomas
    • 1
  1. 1.Department of PathologySt. John’s Medical CollegeBangaloreIndia

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