Synthesis and Secretion of Glycoproteins by Isolated Rat Small Intestinal Epithelial Cells

  • Tony Howe
  • Peter J. Winterburn
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 144)


Mucins are synthesised by the goblet cells of the small intestinal mucosa and secreted into the lumen. Subcellular fractions from rat small intestinal mucosa incorporate glucosamine into brush border glycoproteins and mucins, which can also be labelled in vivo (Forstner, 1970). Human small intestinal mucosa biopsy samples have been cultured and shown to produce mucins (Browning and Trier, 1969).


Sialic Acid Goblet Cell Alcian Blue Small Intestinal Mucosa Cell Brush 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Tony Howe
    • 1
  • Peter J. Winterburn
    • 1
  1. 1.Department of BiochemistryUniversity CollegeCardiffUK

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