Abstract
Gastric mucus is secreted as a discrete gel phase which is not readily soluble in its aqueous environment. Previous studies (Allen, 1977) have demonstrated that the gel matrix is formed by non-covalent interactions between glycoprotein molecules of 2 × 106 molecular weight. In the present work we have used mechanical spectroscopy to study the structure and properties of native gel taken directly from the surface of the gastric mucosa and the gel reconstituted from the isolated glycoprotein purified by gel filtration on Sepharose 4B.
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Literature
Allen, A. 1977, In Mucus in Health & Disease, edited by M. Elstein & D.V. Parke, pp. 275–299 Plenum Press, New York.
Morris, E.R., Rees, D.A. & Welsh, E.J., 1980, J. Mol. Bio1.137.
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© 1982 Plenum Press, New York
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Bell, A.E., Allen, A., Morris, E., Rees, D.A. (1982). Rheological Studies on Native Pig Gastric Mucus Gel. In: Chantler, E.N., Elder, J.B., Elstein, M. (eds) Mucus in Health and Disease—II. Advances in Experimental Medicine and Biology, vol 144. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9254-9_11
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DOI: https://doi.org/10.1007/978-1-4615-9254-9_11
Publisher Name: Springer, Boston, MA
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