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Rheological Studies on Native Pig Gastric Mucus Gel

  • Alan E. Bell
  • Adrian Allen
  • Edwin Morris
  • David A. Rees
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 144)

Abstract

Gastric mucus is secreted as a discrete gel phase which is not readily soluble in its aqueous environment. Previous studies (Allen, 1977) have demonstrated that the gel matrix is formed by non-covalent interactions between glycoprotein molecules of 2 × 106 molecular weight. In the present work we have used mechanical spectroscopy to study the structure and properties of native gel taken directly from the surface of the gastric mucosa and the gel reconstituted from the isolated glycoprotein purified by gel filtration on Sepharose 4B.

Keywords

Hyaluronic Acid Rheological Study Gastric Mucosal Damage Gastric Mucus Mechanical Spectroscopy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature

  1. Allen, A. 1977, In Mucus in Health & Disease, edited by M. Elstein & D.V. Parke, pp. 275–299 Plenum Press, New York.Google Scholar
  2. Morris, E.R., Rees, D.A. & Welsh, E.J., 1980, J. Mol. Bio1.137.Google Scholar

Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • Alan E. Bell
    • 1
    • 2
  • Adrian Allen
    • 1
    • 2
  • Edwin Morris
    • 2
  • David A. Rees
    • 2
  1. 1.Department of PhysiologyUniversity of Newcastle upon TyneUK
  2. 2.Unilever Research Colworth HouseSharnbrookUK

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