Abstract
Electrical impulses of definite intensity, when applied to the cortical surface under deep anaesthesia, elicit an electrical response, which consists of two negative components: 1. a dendritic potential which represents excitatory postsynaptic potentials (EPSPs) of apical dendrites, and/or 2. a slow negative potential (SNP) which has been suggested to result from additional postsynaptic depolarization of either apical dendrites (Goldring and O’Leary, 1960) or afferent fibres (Eccles, 1963). Alternative explanations of the nature of the latter component are hyperpolarization of the pyramidal cell somata in the depth (Li and Chou, 1962) or depolarization of glial cells due to increased extracellular potassium concentration [K+]e following neuronal activity (Roitbak, 1963). The latter assumption was tested in the present study by comparing the time course of the SNP with the time course of [K+]e transients elicited by single direct cortical stimuli.
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© 1981 Plenum Press, New York
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Roitbak, A.I., Machek, J., Pavlík, V., Bobrov, A.V., Otcherashvili, I.V. (1981). The Slow Component of the Direct Cortical Response and Extracellular Potassium. In: Syková, E., Hník, P., Vyklický, L. (eds) Ion-Selective Microelectrodes and Their Use in Excitable Tissues. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9224-2_29
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DOI: https://doi.org/10.1007/978-1-4615-9224-2_29
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