Abstract
The use of ion sensitive microelectrodes (ISMs) has made it possible to obtain virtually real time measurements of extracellular ionic events in mammalian brain during a variety of experimental conditions (see Lux, 1974; Somjen, 1979 for reviews). Data emphasize that the concentrations of ionic species vary considerably during physiological and electrical stimulation, and that these changes have specific distributions which appear to depend on the anatomic organization of the structures studied (see also Moody et al., 1974; Nicholson et al., 1978, and others). Two important questions with respect to these ionic shifts relate to 1) their source in terms of the varieties and distributions of conductances in neuronal membranes and 2) their potential capacity to influence the excitability of stimulated, and nearby non-stimulated, neuronal elements.
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References
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© 1981 Plenum Press, New York
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Prince, D.A., Benninger, C., Kadis, J. (1981). Evoked Ionic Alterations in Brain Slices. In: Syková, E., Hník, P., Vyklický, L. (eds) Ion-Selective Microelectrodes and Their Use in Excitable Tissues. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9224-2_27
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DOI: https://doi.org/10.1007/978-1-4615-9224-2_27
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