Abstract
Neuronal activity causes potassium ions to accumulate in the extracellular space of the spinal cord. Their concentration may increase from the resting level of 2 or 3 mmo1/1 to as high as 9–10 mmo1/l following tetanic stimulation of the dorsal roots or peripheral nerves (Vyklický et al., 1972; Krnjević and Morris, 1972; Kříž et al., 1974; Bruggencate et al., 1974; Somjen and Lothman, 1974; Kříž et al., 1975; Krnjević and Morris, 1975; Syková et al., 1976). Smaller increases, not exceeding 1 mmo1/1 are produced by adequate stimulation of the skin (Syková et al., 1980).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Baylor, D.A., and Nicholls, J.G., 1969, Changes in extracellular potassium concentration produced by neuronal activity in the central nervous system of the leech, J. Physiol., 203:555.
Bruggencate, G., ten, Lux, H.D., and Liebl, L., 1974, Possible relationship between extracellular potassium activity and presynaptic inhibition in the spinal cord of the cat, Pflügers Arch., 349:301.
Eccles, J.C., 1964, “The Physiology of Synapses”, Springer Verlag, Berlin.
Glynn, I.M., and Carlish, S.J.D., 1975, The sodium pump, Physiol. Re. 37:13.
Kříž, N., Sykové, E., Ujec, E., and Vyklický, L., 1974, Changes of extracellular K+ concentration induced by neuronal activity in the spinal cord of the cat, J. Physiol., 238:1.
Kříž, N., Sykové, E., and Vyklický, L., 1975, Extracellular potassium changes in the spinal cord of the cat and their relation to slow potentials, active transport and impulse transmission, J. Physiol., 249:167.
Krnjević, K., and Morris, M.E., 1972, Extracellular K+ activity and slow potential changes in spinal cord and medulla, Can. J. Phys i o1. Pharmaco., 50:1214.
Krnjević, K., and Morris, M.E., 1975, Factors determining the decay K+ potentials in the central nervous system, Can. J. Physiol. Pharmaco., 53:923.
Liley, A.W., 1956, The effect of presynaptic polarization on the spontaneous activity at the mammalian neuromuscular junction, J. Physiol., 134:427.
Nicoll, R.A., 1979, Dorsal root potentials and changes in extracellular potassium in the spinal cord of the frog, J. Physiol., 290:113.
Somjen, G.G., and Lothman, E.W., 1974, Potassium sustained focal potentials of the mammalian spinal cord, Brain Res., 69:153.
Sykové, E., Czéh, G., and Kříž, N., 1980, Potassium accumulation in the frog spinal cord induced by nociceptive stimulation of the skin, Neuroscience Lett., 17:253.
Sykové, E., and Orkand, R.K., 1980, Extracellular potassium accumulation and transmission in frog spinal cord, Neuroscienc., 5:1421.
Sykové, E., Shirayev, B., Kříž, N., Vyklický, L., 1976, Accumulation of extracellular potassium in the spinal cord of frog, Brain Res., 106:413.
Sykové, E., and Vyklický, L., 1978, Effects of picrotoxin on potassium accumulation and dorsal root potentials in the frog spinal cord, Neuroscienc., 3:1061.
Vizi, E.,S., and Vyskočil, F., 1979, Changes in total and quantal release of acetylcholine in the mouse diaphragm during activation and inhibition of membrane ATPase, J. Physiol., 286:1.
Vyklický, L., and Sykové, E., 1980, The effects of increased etracellular potassium in the isolated spinal cord on the flexor reflex of the frog, Neuroscience Lett., 19:203.
Vyklický, L., Sykové, E., Kříž, N., and Ujec, E., 1972, Post-stimulation changes of extracellular potassium concentration in the spinal cord of the rat, Brain Res., 45:608.
Vyklický, L., Sykové, E., and Mellerová, B., 1976, Depolarization of primary afférents in the frog spinal cord under high Mg++ concentrations, Brain Res., 117:153.
Weight, F.F., and Erulkar, S.D., 1976, Modulation of synaptic transmitter release by repetitive postsynaptic action potentials, Scienc., 193:1023.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1981 Plenum Press, New York
About this chapter
Cite this chapter
Vyklický, L., Syková, E. (1981). Effects of Increased Extracellular Potassium Activity in the Frog Spinal Cord on the Flexor Reflex. In: Syková, E., Hník, P., Vyklický, L. (eds) Ion-Selective Microelectrodes and Their Use in Excitable Tissues. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9224-2_19
Download citation
DOI: https://doi.org/10.1007/978-1-4615-9224-2_19
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4615-9226-6
Online ISBN: 978-1-4615-9224-2
eBook Packages: Springer Book Archive