Abstract
Calcium activated membrane permeabilities appear usually as a consequence of calcium currents. To correlate the dynamics of Ca-entry with its effects one would wish to have a measure of steady state and transient changes of intracellular free Ca ([Ca]i). Estimates by various methods suggest that the resting level of [Ca]i is at least 5 orders of magnitude lower than the value expected from a passive distribution (for review see Ashley and Campbell, 1979). Even if the increase in [Ca]i during excitation is small in absolute terms, it may be a large relative change compared to the low background level and may have an important messenger function.
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© 1981 Plenum Press, New York
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Lux, H.D., Hofmeier, G., Aldenhoff, J.B. (1981). Intracellular Free Calcium Affects Electric Membrane Properties. A Study with Calcium-Selective Microelectrodes and with Arsenazo III in Helix Neurons. In: Syková, E., Hník, P., Vyklický, L. (eds) Ion-Selective Microelectrodes and Their Use in Excitable Tissues. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9224-2_10
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DOI: https://doi.org/10.1007/978-1-4615-9224-2_10
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