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Aspects of Radiation-Induced Mutagenesis and Malignant Transformation

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Trends in Photobiology

Abstract

Somatic cell mutation has long been considered as being invol ved in the carcinogenic process either of hereditary nature or induced by physical and chemical agents1–3. The mutation theory is essentially supported by a) The parallels between mutagenic and carcinogenic agents4, b) The hereditary nature of certain tumors such as retinoblastoma, multiple polyposis of the colon and neurofibromatosis that are transmitted as autoromal dominant mutations, c) The association between cancer proneness and high induced mutability in vitro such as in Xeroderma pigmentosum5–6.

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Author information

Authors and Affiliations

  1. Institut Curie, Biologie, Centre Universitaire, Bâtiment 110, 91405, Orsay, France

    Ethel Moustacchi

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  1. Ethel Moustacchi
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Editors and Affiliations

  1. Laboratoire de Biophysique, INSERM U201, Muséum National d’Histoire Naturelle, Paris, France

    C. Hélène  & Th. Montenay-Garestier  & 

  2. Centre de Biophysique Moléculaire, CNRS, Orléans, France

    C. Hélène  & M. Charlier  & 

  3. Laboratoire de Physique, Faculté de Pharmacie, Université Louis Pasteur, Strasbourg, France

    G. Laustriat

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© 1982 Plenum Press, New York

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Moustacchi, E. (1982). Aspects of Radiation-Induced Mutagenesis and Malignant Transformation. In: Hélène, C., Charlier, M., Montenay-Garestier, T., Laustriat, G. (eds) Trends in Photobiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9203-7_18

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  • DOI: https://doi.org/10.1007/978-1-4615-9203-7_18

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9205-1

  • Online ISBN: 978-1-4615-9203-7

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