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Host Defense Mechanisms in Protein Energy Malnutrition

  • Chapter
Diet and Resistance to Disease

Abstract

Protein-energy malnutrition (PEM) is one of the more prevalent conditions in the world. A recent estimate indicated that perhaps one quarter of the worlds population could be considered to be malnourished (World Food and Nutrition Study, 1977). The vast majority suffer from undernutrition; however, an important and probably increasing percentage are overly nourished and there is reason to suspect that if too little is not good, too much may not be any better. Nutritional status, then, spans a wide spectrum of states of inadequacy, adequacy, and excess of which a limited segment is conducive to good or optimal physiological functioning. There is, in a sense, a middle way, for excess in either direction may lead to physiological changes or frank disease. However, this middle way is not necessarily midway between starvation and bulemia, but may rather be somewhat to the left of our current standards for weight, height, or dietary intake. This chapter will examine the relationship between nutritional state and immune function in human PEM in the undernourished of both mild-moderate and severe degree.

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Authors and Affiliations

  1. Tufts-New England Medical Center, 136 Harrison Avenue, Boston, Massachuetts, 02111, USA

    Gerald T. Keusch M.D. (Chief, Division of Geographic Medicine and Professor of Medicine)

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  1. Gerald T. Keusch M.D.
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  1. U.S. Department of Agriculture Science and Education Administration—Agricultural Research, National Animal Disease Center, Ames, Iowa, 50010, USA

    Marshall Phillips  & Albert Baetz  & 

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© 1981 Plenum Press, New York

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Keusch, G.T. (1981). Host Defense Mechanisms in Protein Energy Malnutrition. In: Phillips, M., Baetz, A. (eds) Diet and Resistance to Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9200-6_10

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  • DOI: https://doi.org/10.1007/978-1-4615-9200-6_10

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