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Dietary Fiber and Carbohydrate Metabolism

  • Chapter
Medical Aspects of Dietary Fiber

Part of the book series: Topics in Gastroenterology ((TGEN))

Abstract

Much of the interest in the relationship of dietary fiber to carbohydrate metabolism has stemmed from the suggestion that diabetes should be included in the long list of Western diseases that are associated with a deficiency of dietary fiber.1 Work in this area has been further stimulated by the results of trials of fiber in the treatment of diabetes. Kiehm et al.2 and Anderson and Ward3 found that when diabetic patients on low doses of insulin were treated with high-carbohydrate, high-fiber diets, insulin requirements were reduced. Jenkins et al.4,5 showed that addition of guar gum to the diet lessened glycosuria in diabetics regardless of insulin dose. Results from Miranda and Horwitz6 indicated that feeding a high-cellulose bread to diabetics flattened the glucose profile throughout the day. These studies opened up the possibility of developing treatments for diabetics aimed at modifying small-intestinal events. They also presented the opportunity to explore and develop the results of such changes in terms of overall carbohydrate metabolism. This, in turn, stimulated work to determine types of dietary fiber which may be most effective in modifying glucose tolerance and in defining the physicochemical properties responsible for these effects. Also, practical questions concerning mode of administration, timing with the meal, and the nature of the best background diet have been raised.

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References

  1. Trowell, H. Dietary fiber, ischaemic heart disease and diabetes mellitus. Froc. Nutr. Soc. 32: 151, 1973.

    Article  CAS  Google Scholar 

  2. Kiehm, T. G., J. W. Anderson, and K. Ward. Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men. Am. J. Clin. Nutr. 29: 895, 1976.

    PubMed  CAS  Google Scholar 

  3. Anderson, J. W., and K. Ward. Long term effects of high carbohydrate high fiber diets on glucose and lipid metabolism; a preliminary report on patients with diabetes. Diab. Care 1: 77, 1978.

    Article  CAS  Google Scholar 

  4. Jenkins, D. J. A., T. M. S. Wolever, T. D. R. Hockaday, A. R. Leeds, R. Howarth, S. Bacon, E. C. Apling, and J. Dilawari. Treatment of diabetes with guar gum: Reduction of urinary glucose loss in diabetics. Lancet 2: 779, 1977.

    Article  PubMed  CAS  Google Scholar 

  5. Jenkins, D. J. A., T. M. S. Wolever, R. Nineham, R. Taylor, G. L. Metz, S. Bacon, and T. D. R. Hockaday. Guar crispbread in the diabetic diet. Br. Med. J. 2: 1744, 1978.

    Article  PubMed  CAS  Google Scholar 

  6. Miranda, P. M., and D. L. Horwitz. High fiber diets in the treatment of diabetes mellitus. Ann. Intern. Med. 88: 482, 1978.

    PubMed  CAS  Google Scholar 

  7. Campbell, C. D. Frequency of diabetes with special respect to diet. In: Diabetes, Proc. 7th Cong. Int. Diab. Fed., Amsterdam, Excerpta Medica, 1971, p. 325.

    Google Scholar 

  8. Haber, J. B., K. W. Heaton, D. Murphy, and L. F. Burroughs. Depletion and disruption of dietary fiber: Effect on satiety, plasma, glucose, and serum insulin. Lancet 2: 679, 1977.

    Article  PubMed  CAS  Google Scholar 

  9. Jeffreys, D. B. The effect of dietary fiber on response to orally administered glucose. Proc. Nutr.Soc. 33: 11A, 1974.

    Google Scholar 

  10. Jenkins, D. J. A., T. M. S. Wolever, A. R. Leeds, M. A. Gassull, P. Haisman, J. Dilawari, D. V. Goff, G. L. Metz, and K. G. M. M. Alberti. Dietary fiber, fiber analogues and glucose tolerance: Importance of viscosity. Br. Med. J. 1: 1392, 1978.

    Article  PubMed  CAS  Google Scholar 

  11. Jenkins, D. J. A., A. R. Leeds, M. A. Gassull, B. Cochet, and K. G. M. M. Alberti. Decrease in postprandial insulin and glucose concentrations by guar and pectin. Ann. Intern. Med. 86: 20, 1977.

    PubMed  CAS  Google Scholar 

  12. Jenkins, D. J. A., A. R. Leeds, M. A. Gassull, T. M. S. Wolever, D. V. Goff, K. G. M. M. Alberti, and T. D. R. Hockaday. Unabsorbable carbohydrates and diabetes: Decreased postprandial hyperglycemia. Lancet 2: 172, 1976.

    Article  PubMed  CAS  Google Scholar 

  13. Wolever, T. M. S., D. J. A. Jenkins, R. Nineham, and K. G. M. M. Alberti. Guar gum and the reduction of postprandial glycemia: Effect of food form and dose. Br. J. Nutr. 41: 505, 1979.

    Article  PubMed  CAS  Google Scholar 

  14. Goulder, T. J., K. G. M. M. Alberti, and D. J. A. Jenkins. Diab. Care, 1: 351, 1978.

    Article  CAS  Google Scholar 

  15. Morgan, L. M., T. J. Goulder, D. Tsioladis, V. Marks, and K. G. M. M. Alberti. The effect of unabsorbable carbohydrate on gut hormones: Modification of postprandial GIP secretion by guar. Diabetalogia 17: 85, 1979.

    Article  CAS  Google Scholar 

  16. Jenkins, D. J. A., A. R. Leeds, S. R. Bloom, D. Sarson, R. Alberquerque, G. L. Metz, and K. G. M. M. Alberti. Pectin and post-gastric surgery compoications: Normalization of postprandial glucose and endocrine responses Gut, 1980 (in press).

    Google Scholar 

  17. Bond, J. R., Jr., and J. D. Levitt. Use of pulmonary hydrogen (H2) measurements to quantitate carbohydrate absorption. J. Clin. Invest. 51: 1219, 1972.

    Article  PubMed  CAS  Google Scholar 

  18. Leeds, A. R., N. Bolster, and A. S. Truswell. Guar gum and glucose absorption: Absence of evidence for malabsorption. Proc. Nutr. Soc. 37:89A, 1978.

    PubMed  CAS  Google Scholar 

  19. Bond, J. H., and M. D. Levitt. Investigation of small bowel transit time utilizing pulmonary hydrogen (H2) measurements. J. Lab. Clin. Med. 85: 546, 1975.

    PubMed  CAS  Google Scholar 

  20. Leeds, A. R., D. N. Ralphs, P. Boulos, F. Ebied, G. L. Metz, J. Dilawari, A. Elliott, and D. J. A. Jenkins. Pectin and gastric emptying in the dumping syndrome. Proc. Nutr. Soc. 37: 23A, 1978.

    PubMed  CAS  Google Scholar 

  21. Leeds, A. R., N. R. Bolster, R. Andrews, and A. S. Truswell. Meal viscosity, gastric emptying and glucose absorption in the rat. Proc. Nutr. Soc. 38: 44A, 1979.

    Article  PubMed  CAS  Google Scholar 

  22. Holt, S., R. C. Heading, D. C. Carter, L. F. Prescott, and P. Tothill. Effect of gel fiber on gastric emptying and absorption of glucose and paracetamol. Lancet 1: 636, 1979.

    Article  PubMed  CAS  Google Scholar 

  23. Jenkins, D. J. A., M. A. Gassull, A. R. Leeds, G. L. Metz, J. B. Dilawari, B. Slavin, and L. M. Blendis. Effect of dietary fiber on complications of gastric surgery: Prevention of postprandial hypoglycemia by pectin. Gastroenterology. 72: 215, 1977.

    Google Scholar 

  24. Aherne, J., Unpublished observations, 1979.

    Google Scholar 

  25. Trowell, H. T. Diabetes mellitus and obesity. In: Refined Carbohydrate Foods and Disease: Some Implications of Dietary Fiber, D. P. Burkitt and H. C. Trowell (eds). London, Academic Press, 1975, p. 246.

    Google Scholar 

  26. Crapo, P. A., G. Reaven, and J. Olefsky, Postprandial plasma-glucose-insulin responses to different complex carbohydrates. Diabetes 26: 1178, 1977.

    Article  PubMed  CAS  Google Scholar 

  27. Jenkins, D. J. A., T. M. S. Wolever, R. Haworth, A. R. Leeds, and T. D. R. Hockaday. Guar gum in diabetes. Lancet 2: 1086, 1976.

    Article  PubMed  CAS  Google Scholar 

  28. Williams, D. R. R., and W. P. T. James. Fiber and diabetes. Lancet 1: 271, 1979.

    Article  PubMed  CAS  Google Scholar 

  29. Jenkins, D. J. A., R. Nineham, C. Craddock, P. Craig-McFeely, K. Donaldson, T. Leigh, and J. Snook. Fiber and diabetes. Lancet 1: 434, 1979.

    Article  Google Scholar 

  30. Dewar, J., P. Garcia-Webb, and G. M. Shenfield. Guar and diabetes. Lancet 1: 612, 1979.

    PubMed  CAS  Google Scholar 

  31. Jenkins, D. J. A., R. Nineham, T. M. S. Wolever, D. V. Goff, J. Ahem, D. Sarson, S. Bloom, K. G. M. M. Alberti, and T. D. R. Hockaday. Effect of eating guar and glucose on subsequent glucose tolerance. Clin. Sci. 57: 26, 1979.

    Google Scholar 

  32. Brodribb, A. G. M., and D. M. Humphreys. Diverticular disease: Three studies. Br. Med. J. 1: 424, 1976.

    Article  PubMed  CAS  Google Scholar 

  33. Jenkins, D. J. A., A. R. Leeds, H. Houston, L. Hinks, K. G. M. M. Alberti, and J. H. Cummings. Carbohydrate tolerance in man after six weeks of pectin administration. Proc. Nutr. Soc. 36: 60A, 1977.

    PubMed  CAS  Google Scholar 

  34. Himsworth, H. P. The dietetic factor determining the glucose tolerance and sensitivity to insulin of healthy man. Clin. Sci. 2: 67, 1935.

    Google Scholar 

  35. Brunzell, J. D., R. L. Learner, and W. R. Hazzard. Improved glucose tolerance with high carbohydrate feeding in mild diabetes. N. Engl. J. Med. 284: 521, 1971.

    Article  PubMed  CAS  Google Scholar 

  36. Weinsier, R. L., A. Seeman, M. G. Herrera, J. P. Assal, J. S. Soeldner, and R. E. Gleason. Higher-lower-carbohydrate diets in diabetes mellitus: Study of effects on diabetic control, insulin secretion and blood lipids. Ann. Intern. Med. 80: 332, 1974.

    PubMed  CAS  Google Scholar 

  37. Hales, C. N. and P. J. Randall. Effects of low carbohydrate diet and diabetes mellitus on plasma glucose, non-esterified fatty acid and insulin during oral glucose tolerance tests. Lancet 1: 790, 1963.

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Nutrition and Food Science, Faculty of Medicine, University of Toronto, Toronto, M5S1A8, Canada

    David J. A. Jenkins

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  1. David J. A. Jenkins
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Editor information

Editors and Affiliations

  1. Syntex Research, Palo Alto, California, USA

    Gene A. Spiller

  2. University of Toronto, Toronto, Ontario, Canada

    Ruth McPherson Kay

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© 1980 Plenum Publishing Corporation

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Jenkins, D.J.A. (1980). Dietary Fiber and Carbohydrate Metabolism. In: Spiller, G.A., Kay, R.M. (eds) Medical Aspects of Dietary Fiber. Topics in Gastroenterology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9176-4_10

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  • DOI: https://doi.org/10.1007/978-1-4615-9176-4_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9178-8

  • Online ISBN: 978-1-4615-9176-4

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