Abstract
Somewhere between 50 and 75 persons per every 1,000,000 population develop end-stage renal disease annually. In view of the extreme expense and in general unsatisfactory response to treatment it would seem highly desirable to prevent rather than treat end - stage kidney disease. It is a well recognized fact that renal calcium-phosphate deposits resulting from a number of clinical conditions including sarcoidosis, milk alkali syndrome, hyper-parathyroidism and vitamin D intoxication can incite an inflammatory and fibrotic response which may ultimately result in total loss of renal function (1–4). Since renal parenchymal calcification is also a common finding in human end-stage kidneys (5–8) irrespective of the primary renal disease it is possible that this promotes further damage to the diseased kidney. It is apparent that renal calcification could have major clinical implications.
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Alfrey, A.C., Karlinsky, M., Haut, L. (1980). Protective Effect of Phosphate Restriction on Renal Function. In: Massry, S.G., Ritz, E., Jahn, H. (eds) Phosphate and Minerals in Health and Disease. Advances in Experimental Medicine and Biology, vol 128. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9167-2_26
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DOI: https://doi.org/10.1007/978-1-4615-9167-2_26
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