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Phosphate and Minerals in Health and Disease pp 89–91Cite as

Tubular Localization of the Effect of 1,25-Dihydroxy-Vitamin D3 and Dietary Phosphate on the Transport of Phosphate in Thyroparathyroidectomized Rats

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 128))

Abstract

Clearance studies in vitamin D-replete thyroparathyroidectomized (TPTX) rats have shown that chronic administration of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3, 2 x 13 pmol/day intraperitoneally for 7 days) decreased the overall tubular capacity to reabsorb inorganic phosphate (Pi) (1). In the present work, the influence of 1,25(OH)2D3 on the tubular handling of Pi was localized by random free-flow micropunctures.

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References

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Authors and Affiliations

  1. Department of Pathophysiology, University of Berne, Murtenstrasse 35, 3010, Berne, Switzerland

    R. Mühlbauer, J.-P. Bonjour & H. Fleisch

Authors
  1. R. Mühlbauer
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  2. J.-P. Bonjour
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  3. H. Fleisch
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Editor information

Editors and Affiliations

  1. University of Southern California, Los Angeles, California, USA

    Shaul G. Massry

  2. University of Heidelberg, Heidelberg, German Federal Republic

    Eberhard Ritz

  3. Louis Pasteur University, Strasbourg, France

    Henri Jahn

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© 1980 Plenum Press, New York

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Mühlbauer, R., Bonjour, JP., Fleisch, H. (1980). Tubular Localization of the Effect of 1,25-Dihydroxy-Vitamin D3 and Dietary Phosphate on the Transport of Phosphate in Thyroparathyroidectomized Rats. In: Massry, S.G., Ritz, E., Jahn, H. (eds) Phosphate and Minerals in Health and Disease. Advances in Experimental Medicine and Biology, vol 128. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9167-2_11

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  • DOI: https://doi.org/10.1007/978-1-4615-9167-2_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9169-6

  • Online ISBN: 978-1-4615-9167-2

  • eBook Packages: Springer Book Archive

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