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Interaction of Hyperuricuria and Hyperoxaluria on Renal Calcium Oxalate Stone Formation

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Purine Metabolism in Man-III

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 122A))

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Abstract

There is increasing evidence that excessive urinary excretion of uric acid plays a role in the genesis of renal calcium oxalate stones. 17 percent of our stone formers show a hyperuricuria, a much higher frequency than in normal people. Robertson (1) describes an inhibitory effect on acid mucopo1ysaccarides, which serve as inhibitors of crystal aggregation.

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Literature

  1. W.G. ROBERTSON, M. PEACOCK and B.E.C. NORDIN Clin. Chim. Acta 43, 31, 1973

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  5. J.L. MEYER, J.H. BERGERT and L.H. SMITH Invest. Urol. 14, 115, 1976

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  6. B. FINLAYSON and F. REID Invest. Urol 15, 489, 1978

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© 1980 Plenum Press, New York

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Hering, F., Bigalke, KH., Lutzeyer, W. (1980). Interaction of Hyperuricuria and Hyperoxaluria on Renal Calcium Oxalate Stone Formation. In: Rapado, A., Watts, R.W.E., De Bruyn, C.H.M.M. (eds) Purine Metabolism in Man-III. Advances in Experimental Medicine and Biology, vol 122A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9140-5_16

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  • DOI: https://doi.org/10.1007/978-1-4615-9140-5_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9142-9

  • Online ISBN: 978-1-4615-9140-5

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