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Tissue Culture Models of In Vivo Interferon Production and Action

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Human Interferon

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 110))

Abstract

Interferon participation in recovery from viral infection is clearly documented by a series of in vitro observations. It has been shown in vitro that the inhibition of interferon production during infection often notably increases the amount of virus produced (Glasgow and Habel 1962). Cultures infected with viruses in conditions favoring good interferon production yield scarce quantities of virus and establishment of inapparent or abortive infections (Isaacs, 1963). The same effect can also be obtained by adding preformed interferon to the infected cultures.

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© 1978 Plenum Press, New York

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Dianzani, F., Viano, I., Santiano, M., Zucca, M., Gullino, P., Baron, S. (1978). Tissue Culture Models of In Vivo Interferon Production and Action. In: Stinebring, W.R., Chapple, P.J. (eds) Human Interferon. Advances in Experimental Medicine and Biology, vol 110. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-9080-4_10

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  • DOI: https://doi.org/10.1007/978-1-4615-9080-4_10

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4615-9082-8

  • Online ISBN: 978-1-4615-9080-4

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