UPD-Galactose: Ceramide Galactosyltransferase. Kinetic Properties and Effect of Detergents and Phospholipids on the Partially Purified Enzyme of Rat Brain

  • N. M. Neskovic
  • P. Mandel
  • S. Gatt
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 101)


UDP-galactose: ceramide galactosyltransferase (CGa1T, EC catalyzes the synthesis of cerebrosides according to the following reaction: UDP-galactose + ceramide → cerebroside + UDPS


Lipid Extract Enzyme Preparation Fraction Versus Enzyme Source Lipid Substrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Basu, S., Schultz, A.M., Basu, M. and Roseman, S. (1971) J. Biol. Chem. 246, 4272–4279.Google Scholar
  2. 2.
    Brenkert, A. and Radin, N.S. (1972) Brain Res. 36, 183–193.PubMedCrossRefGoogle Scholar
  3. 3.
    Costantino-Ceccarini, E. and Suzuki, K. (1975) Arch. Biochem. Biophys. 167, 646–654.Google Scholar
  4. 4.
    Gatt, S. (1973) in Metabolic Inhibitors (Hochster, R.M., Kates, M. and Quastel, J.H., eds) Vol. IV, pp. 349–387, Academic Press, N.Y.Google Scholar
  5. 5.
    Gottesdiner, T. and Gatt, S. (1977) Israel J. Med. Sci., in press.Google Scholar
  6. 6.
    Leíbovitz-Ben Gershon, Z., Kobiler, I. and Gatt, S. (1972) J. Biol. Chem. 247, 6840–6847.Google Scholar
  7. 7.
    Morell, P. and Radin, N.S. (1969) Biochemistry 8, 506–512.PubMedCrossRefGoogle Scholar
  8. 8.
    Neskovic, N.M., Nussbaum, J.L. and Mandel, P. (1970) FEBS Lett. 8, 213–216.PubMedCrossRefGoogle Scholar
  9. 9.
    Neskovic, N.M., Sarliève, L.L. and Mandel, P. (1972) Brain Res. 42, 147–157.PubMedCrossRefGoogle Scholar
  10. 10.
    Neskovic, N.M., Sarliève, L.L. and Mandel, P. (1974) Biochim. Biophys. Acta, 334, 309–315.Google Scholar
  11. 11.
    Neskovic, N.M., Sarliève, L.L. and Mandel, P. (1976) Biochim. Biophys. Acta 429, 342–351.Google Scholar
  12. 12.
    Small, D.M. (1970) Federation Proc. 29, 1320–1326.Google Scholar
  13. 13.
    Yedgar, S., Hertz, R. and Gatt, S. (1974) Chem. Phys. Lipids 13, 404–414.Google Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • N. M. Neskovic
    • 1
  • P. Mandel
    • 1
  • S. Gatt
    • 2
  1. 1.Centre de Neurochimie du CNRSStrasbourgFrance
  2. 2.Laboratory of Neurochemistry, Department of BiochemistryThe Hebrew University, Hadassah Medical SchoolJerusalemIsrael

Personalised recommendations