Cholesterol Oxidase as a Probe for Studying Membrane Composition and Organization

  • Y. Barenholz
  • E. J. Patzer
  • N. F. Moore
  • R. R. Wagner
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 101)


Lipid bilayers of biological membranes often contain sterols (mainly cholesterol) as a major component. Membrane cholesterol content has been examined in some detail and is often quantitated in relation to phospholipid concentration. The ratio of cholesterol to phospholipid appears to affect many physical and biological properties of a membrane (Cooper, 1977). Several model membrane systems are now providing a better understanding of the interaction at the molecular level of cholesterol and various phospholipids (Huang, 1977; Thompson and Huang, 197 8; Demel and DeKruijff, 1976). Such information may provide better insight into biological functions of cell membranes.


Biological Membrane Cholesterol Oxidase Membrane Cholesterol Cholesterol Oxidation Viral Membrane 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Y. Barenholz
    • 1
    • 2
  • E. J. Patzer
    • 3
  • N. F. Moore
    • 3
  • R. R. Wagner
    • 3
  1. 1.Departments of Biochemistry, Schools of MedicineHebrew UniversityJerusalemIsrael
  2. 2.University of VirginiaCharlottesvilleUSA
  3. 3.Department of MicrobiologyUniversity of VirginiaCharlottesvilleUSA

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