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Purification and Partial Characterization of Human Liver α-Galacto-Sidase: Is α-Galactosidase B an α-N-Acetylgalactosaminidase?

  • Kenneth J. Dean
  • Sung Sang J. Sung
  • Charles C. Sweeley
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 101)

Abstract

One of the most interesting aspects of lysosomal glycolipid hydrolases is the specificity (or lack thereof) of their interactions with artificial substrate analogs and glycosphingolipid substrates. This is of particular importance with respect to multiple forms of these glycosidases, which may arise as artifacts from partial degradation during purification or may be due to chemical differences such as subunit composition or microheterogeneity of the carbohydrate moieties.

Keywords

Sialic Acid Multiple Form Carbohydrate Moiety Porcine Liver Pyranose Ring 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Kenneth J. Dean
    • 1
  • Sung Sang J. Sung
    • 1
  • Charles C. Sweeley
    • 1
  1. 1.Department of BiochemistryMichigan State University East LansingMichiganUSA

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