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Membrane-Bound Base-Exchange Reactions in Animal Tissues

  • Giuseppe Porcellati
  • Alberto Gaiti
  • Helmut Woelk
  • Gianna Evelina de Medio
  • Marina Brunetti
  • Ermelinda Francescangeli
  • Gianfranco Trovarelli
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 101)

Abstract

A number of investigators have recently studied in vitro the Ca2+ -stimulated, non-energy-dependent, base-exchange incorporation of nitrogenous bases, as ethanolamine, choline and L-serine, into corresponding phospholipids (see 1 and 2). The enzymic system, called base-exchange, has been extensively studied in nervous tissues (3–8), and plays an interesting role in changing the molecular structure of the polar head groups of membrane-bound phospholipids(7,8). Experimental data from various laboratories (3,7–11) support the conclusion that more than one enzyme is involved in the exchange reactions in animal tissues (see 1 and 2).

Keywords

Adenylate Cyclase Activity Small Pool Displacement Reaction Synaptic Membrane Gaba Uptake 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Giuseppe Porcellati
    • 1
  • Alberto Gaiti
    • 1
  • Helmut Woelk
    • 2
  • Gianna Evelina de Medio
    • 1
  • Marina Brunetti
    • 1
  • Ermelinda Francescangeli
    • 1
  • Gianfranco Trovarelli
    • 1
  1. 1.Istituto di BiochimicaUniversità di PerugiaPerugiaItaly
  2. 2.Neurochemische AbteilungUniversität NervenklinikErlangen (Saar)West Germany

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