Abstract
A number of investigators have recently studied in vitro the Ca2+ -stimulated, non-energy-dependent, base-exchange incorporation of nitrogenous bases, as ethanolamine, choline and L-serine, into corresponding phospholipids (see 1 and 2). The enzymic system, called base-exchange, has been extensively studied in nervous tissues (3–8), and plays an interesting role in changing the molecular structure of the polar head groups of membrane-bound phospholipids(7,8). Experimental data from various laboratories (3,7–11) support the conclusion that more than one enzyme is involved in the exchange reactions in animal tissues (see 1 and 2).
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References
G.Arienti, M.Brunetti, A.Gaiti, P.Orlando and G.Porcellati; In Function and Metabolism of Phospholipids in the Central and Peripheral Nervous Systems (G.Porcellati, L.Amaducci and C.Galli, eds. ), Plenum Press, N.Y., 1976, pp. 63–78.
G.Porcellati, M.Brunetti, A.Gaiti, G.E.De Medio, E.Francescangeli and G.Trovarelli; In Function and Biosynthesis of Lipids (R. Brenner, N.G.Bazan and N.Giusto, eds. ), Plenum Press, N.Y., 1977, pp. 476–491.
G.Porcellati, G.Arienti, M.Pirotta and D.Giorgini; J.Neurochem. 18: 1395–1417 (1971).
J.N.Kanfer; J.Lipid Res. 13: 468–476 (1972).
E.K.Miller and R.M.C.Dawson; Biochem.J. 126: 805–821 (1972).
G.Goracci, Ch.Blomstrand, G.Arienti, A.Hamberger and G.Porcellati; J.Neurochem. 20: 1167–1180 (1973).
A.Gaiti, G.E.De Medio, M.Brunetti, L.Amaducci and G.Porcellati; J.Neurochem. 23: 1153–1159 (1974).
A.Gaiti, M.Brunetti, H.Woelk and G.Porcellati; Lipids 11: 823–829 (1976).
K.S.Bjerve; Biochim.Biophys.Acta 306: 396–402 (1973).
M.Saito, E.Bourque and J.Kanfer; Arch.Biochem.Biophys. 169: 304–310 (1975).
M.Saito, E.Bourque and J.Kanfer; Arch.Biochem.Biophys. 164: 420428 (1974).
T.Miura and J.Kanfer; Arch.Biochem.Biophys. 175: 654–661 (1976).
E.Yavin and B.P.Zeigler; J.Biol.Chem. 252: 260–267 (1977).
A.Gaiti, M.Brunetti and G.Porcellati; FEBS Letters 49: 361–364 (1975).
R.Sellström and A.Hamberger; J.Neurochem. 24: 847–852 (1975).
A.Hamberger, H.A.Hansson: and L.Sellström; Exp.Cell Res. 92: 1–10 (1975).
C.W.Cotman and D.A.Matthews; Biochim.Biophys.Acta 249: 380–394 (1971).
A.Hamberger and L.Svennerholm; J.Neurochem. 18: 1821–1829 (1971).
G.E.De Medio, X.Sellström, A.Hamberger and G.Porcellati; Neurochem.Res. in press.
E.De Robertis, G.R.D.L.Arnaiz, M.Alberici, R.W.Butcher and E.W. Sutherland; J.Biol.Chem. 242: 3487–3496 (1967).
J.P.Perkins; in Advances in Cyclic Nucleotide Research (P.Green gard and G.A.Robinson, eds.), Raven Press, New York, 1973, 1–64.
K. von Hungen and S.Roberts; in Reviews of Neurosciences (S. Ehrenpreis and J.Kopin, eds.), vol.I, Raven Press, New York, 1974.
A.Steiner, A.Pagliaro, L.R.Chase and D.M.Kipnis; J.Biol.Chem. 247: 1114–1120 (1972).
S.L.Pohl, H.M.J.Krans, V.Kozireff, L.Birmbaumer and M.Rodbell; J.Biol.Chem. 240: 4447–4454 (1971).
A.Rethy, V.Tomasi, A.Trevisani and O.Barnabei; Biochim.Biophys. Acta 290: 58–65 (1972).
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Porcellati, G. et al. (1978). Membrane-Bound Base-Exchange Reactions in Animal Tissues. In: Gatt, S., Freysz, L., Mandel, P. (eds) Enzymes of Lipid Metabolism. Advances in Experimental Medicine and Biology, vol 101. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9071-2_28
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DOI: https://doi.org/10.1007/978-1-4615-9071-2_28
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