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Membrane-Bound Base-Exchange Reactions in Animal Tissues

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Enzymes of Lipid Metabolism

Abstract

A number of investigators have recently studied in vitro the Ca2+ -stimulated, non-energy-dependent, base-exchange incorporation of nitrogenous bases, as ethanolamine, choline and L-serine, into corresponding phospholipids (see 1 and 2). The enzymic system, called base-exchange, has been extensively studied in nervous tissues (3–8), and plays an interesting role in changing the molecular structure of the polar head groups of membrane-bound phospholipids(7,8). Experimental data from various laboratories (3,7–11) support the conclusion that more than one enzyme is involved in the exchange reactions in animal tissues (see 1 and 2).

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© 1978 Plenum Press, New York

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Porcellati, G. et al. (1978). Membrane-Bound Base-Exchange Reactions in Animal Tissues. In: Gatt, S., Freysz, L., Mandel, P. (eds) Enzymes of Lipid Metabolism. Advances in Experimental Medicine and Biology, vol 101. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9071-2_28

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  • DOI: https://doi.org/10.1007/978-1-4615-9071-2_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-9073-6

  • Online ISBN: 978-1-4615-9071-2

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