The Role of Phosphatidylglycerol as a Donor of Phosphatidyl and of sn-Glycerol-1-Phosphate Groups in Biosynthetic Reactions

  • Ronald A. Pieringer
  • J. Michael Shaw
  • Mong-Ching W. Ganfield
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 101)


Recent experiments from a number of laboratories have provided evidence that phosphatidylglycerol (PG) can function as a donor of either a phosphatidyl or a glycerol phosphate moiety in de novo biosynthetic reactions. In contrast to a simple exchange reaction the transfer of these groups from PG results in the net formation of a new product which the organism in most cases cannot make by alternate reactions. Systems which use PG in this way as yet have been conclusively demonstrated only in bacteria.


Glycerol Phosphate Hydrogen Fluoride Lipoteichoic Acid Phosphodiester Bond Biosynthetic Reaction 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Ronald A. Pieringer
    • 1
  • J. Michael Shaw
    • 1
  • Mong-Ching W. Ganfield
    • 1
  1. 1.Department of BiochemistryTemple University School of MedicinePhiladelphiaUSA

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