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A Comparative Analysis of the Effects of Narcotics, Alcohol and the Barbiturates on the Hypothalamic-Pituitary-Gonadal Axis

  • Theodore J. Cicero
  • Thomas M. Badger
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 85B)

Abstract

The purpose of this paper is to provide an overview of our current state of knowledge regarding the effects of alcohol, the narcotics and the barbiturates on the hypothalamic-pituitary-gonadal axis in the male. Three facets of this problem will be considered: acute drug effects; chronic effects, particularly with respect to the development of tolerance and physical dependence; and, finally, an attempt will be made to indicate the way in which these three substances of abuse are similar and/or dissimilar in their effects on this system. The effects of acute and chronic treatment with narcotics, alcohol and the barbiturates will be discussed first and then an attempt will be made, in a General Discussion, to summarize the data, make general comparisons between the drugs and suggest future lines of research.

Keywords

Luteinizing Hormone Testosterone Level Serum Testosterone Serum Testosterone Level Luteinizing Hormone Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Theodore J. Cicero
    • 1
  • Thomas M. Badger
    • 1
  1. 1.Department of PsychiatryWashington University School of MedicineSt. LouisUSA

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