Self-Administration of Sedatives by Humans
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Sedative drugs have many of the same effects as alcohol. Taken in high doses, both produce confusion, difficulty in thinking, emotional lability, and motor incoordination (Isbell et al., 1950). Both also have a high potential for abuse, with tolerance and physiological dependence resulting from chronic, high-dose use (Wikler, 1968). In experimental studies of human alcohol and sedative intoxication, clinical symptoms of intoxication and withdrawal were similar for both compounds, with alcohol substituting for and maintaining physiological dependence previously established to sedative compounds (Fraser et al., 1957).
KeywordsSedative Drug Slur Speech Preference Ratio Drug Serum Level Motor Incoordination
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