Alteration of Ethanol Preference in Hamsters: Effects of Photoperiod and 5-Hydroxytryptophan

  • Irving Geller
  • Roy J. Hartmann
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 85B)


Relatively few investigators have made use of the golden hamster as an experimental animal for ethanol studies. This is somewhat surprising insofar as hamsters show a marked preference for ethanol solutions in free-choice experiments. Given a choice of water or a 10% ethanol solution, hamsters will drink 88% of their total fluid as ethanol solution (Arvola and Forsander, 1961). Furthermore, the most preferred concentration of ethanol for the male hamster is 15% (Arvola and Forsander, 1963) in contrast to the rat that shows a preference only for much lower ethanol concentrations.


Ethanol Solution Pineal Gland Ethanol Intake Total Darkness Male Hamster 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Arvola, A. and Forsander, O. Comparison between water and alcohol consumption in six animal species in free-choice experiments. Nature 191:819–820, 1961.CrossRefGoogle Scholar
  2. Arvola, A. and Forsander, O. Hamsters in experiments of free choice between alcohol and water. Quart. J. Stud. Alc. 24:591–597, 1963.Google Scholar
  3. Geller, I. Ethanol preference in the rat as a function of photoperiod. Science 173:456–459, 1971.CrossRefGoogle Scholar
  4. Hoffman, R.A. and Reiter, R.J. Pineal glands: influence on gonads of male hamsters. Science 148:1609–1611, 1965.CrossRefGoogle Scholar
  5. Myers, R.D. and Holman, R.B. A procedure for eliminating position habits in preference--aversion tests for ethanol and other fluids. Psychon. Sci. 6:235–236, 1966.Google Scholar
  6. Myers, R.D. Voluntary alcohol consumption in animals: peripheral and intracerebral factors. Psychosom. Med. 28:484–497, 1966.Google Scholar
  7. Rusak, B. and Zucker, I. Fluid intake of rats in constant light and during feeding restricted to the light or dark portion of the illumination cycle. Physiol. Behav. 13:91–100, 1974.CrossRefGoogle Scholar
  8. Wurtman, R.J., Axelrod, J. and Phillips, L.S. Melatonin synthesis in the pineal gland: control by light. Science 142:1071–1073, 1963.CrossRefGoogle Scholar
  9. Wurtman, R.J., Axelrod, J. and Fischer, J.E. Melatonin synthesis in the pineal gland: effect of light mediated by the sympathetic nervous system. Science 143:1328–1329, 1964.CrossRefGoogle Scholar
  10. Wurtman, R.J., Axelrod, J. and Kelly, D.E. The Pineal pp. 199. New York, Academic Press, 1968.Google Scholar
  11. Geller, I. Effect of para-chlorophenylalanine and 5-hydroxytryptophan on alcohol intake in the rat. Pharmacol. Biochem. Behav. 1(3): 361–365, 1973.CrossRefGoogle Scholar
  12. Mclsaac, W.M. and Estevez, V. Structure-action relationship of β-carbolines as monoamine oxidase inhibitors. Biochem. Pharmacol. 15:1625–1627, 1966.CrossRefGoogle Scholar
  13. Ho, B.T., Mclsaac, W.M. and Tansey, L.W. Inhibitors of monoamine oxidase IV: 6 (or 8) substituted tetrahydro-3-carbolines and their 9-methyl analogues. J. Pharm. Sci. 58:998–1001, 1969.CrossRefGoogle Scholar
  14. Ho, B.T., McIsaac, W.M., Walker, K.R. and Estevez, V. Inhibitors of monoamine oxidase. Influence of methyl substitution on the inhibitory activity of ß-carbolines. J. Pharm. Sci. 57:269–273, 1968.CrossRefGoogle Scholar
  15. Geller, I. and Purdy, R. Alteration of ethanol preference in rats; effects of ß-carbolines. Adv. Exp. Med. Biol. 59:295–301, 1975.Google Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Irving Geller
    • 1
  • Roy J. Hartmann
    • 1
  1. 1.Southwest Foundation for Research and EducationSan AntonioUSA

Personalised recommendations